Summary
Calf kidney cells were found to be susceptible to seven representative strains of influenza virus (two type A, two type A1, one type A2, one type B, and the virus of Swine influenza).
A quantal assay system, based on cytopathic effect, haemadsorption, or haemagglutination, has been developed. It is at least as sensitive as assay in whole eggs. One strain of virus, FM 1, required passage in calf kidney cells before attaining maximal infectivity for them.
Similar content being viewed by others
References
Anderson, S. G.: Austral. J. Exper. Biol.25, 243 (1947).
Burnet, F. M.: Med. J. Australia II, 1935, 651.
Crawford, J. G.: Proc. Soc. Exper. Biol. Med.97, 341 (1958).
Eagle, H.: Science130, 432 (1959).
Fazekas de St. Groth, S.: J. Hyg.53, 276 (1955).
Fazekas de St. Groth, S., andD. O. White: J. Hyg.56, 151 (1958).
Fazekas de S. Groth, S., andD. O. White: J. Hyg.56, 535 (1958).
Francis, T.: Science80, 457 (1934).
Francis, T.: Science92, 405 (1940).
Green, I. J., M. Lieberman, andW. J. Mogabgab: J. Immunol.78, 233 (1957).
Haas, K., andH. Wulff: Zschr. Hyg.143, 568 (1957).
Hanks, J. H., andR. E. Wallace: Proc. Soc. Exper. Biol. Med.71, 196 (1949).
Hinz, R. W., andJ. T. Syverton: Proc. Soc. Exper. Biol. Med.101, 22 (1959).
Laver, W. G.: Virology14, 499 (1961).
Laver, W. G.: Virology18, 19 (1962).
Lehmann-Grube, F.: Arch. ges. Virusforsch.11, 258 (1961).
Lehmann-Grube, F.: Arch. ges. Virusforsch.14, 1 (1963).
Lim, K. A., A. Smith, J. H. Hale, andJ. Glass: Lancet,II, 1957, 791.
Melnick, J. L.: Ann. N. Y. Acad. Sci.61, 754 (1955).
Morgan, J. F., H. J. Morton, andR. C. Parker: Proc. Soc. Exper. Biol. Med.73, 1 (1950).
Rappaport, C.: Bull. W.H.O.14, 147 (1956).
Rasmussen, A. F., J. C. Stokes, andJ. E. Smadel: Amer. J. Hyg.47, 142 (1948).
Shope, R. E.: J. Exper. Med.54, 349 (1931).
Vogel, J., andA. Shelokov: Science126, 358 (1957).
White, D. O., andS. Fazekas de St. Groth: J. Hyg.57, 123 (1959).
Wulff, H., andR. Haas: Behringwerk-Mitt., Marburg,33, 64 (1957).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Lehmann-Grube, F. Influenza viruses in cell cultures. Archiv f Virusforschung 14, 177–188 (1964). https://doi.org/10.1007/BF01555090
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF01555090