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Influenza viruses in cell cultures

II. Use of calf kidney cells for quantal assay

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Summary

Calf kidney cells were found to be susceptible to seven representative strains of influenza virus (two type A, two type A1, one type A2, one type B, and the virus of Swine influenza).

A quantal assay system, based on cytopathic effect, haemadsorption, or haemagglutination, has been developed. It is at least as sensitive as assay in whole eggs. One strain of virus, FM 1, required passage in calf kidney cells before attaining maximal infectivity for them.

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Lehmann-Grube, F. Influenza viruses in cell cultures. Archiv f Virusforschung 14, 177–188 (1964). https://doi.org/10.1007/BF01555090

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  • DOI: https://doi.org/10.1007/BF01555090

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