Abstract
Follow-up data on 57 schizophrenic patients, including 25 boys and 32 girls between the ages of 7 and 13, is reported. Average length of follow-up was 15 years. Symptoms found in children under 10 and in prepubertal cases are described. Cases with acute, relapsing episodes occurred more often than chronic cases, but before age 11 acute cases were less frequent. Twenty percent of the patients recovered completely, 30% reached a relatively good social adjustment, and 50% had moderate or poor remission. Family incidence of psychiatric disorders had no influence on prognosis, nor did unfavorable family environment. Premorbid personality development was, however, found to be of prognostic value. Prodromal episodes occurred in 55% of the cases, and 65% of the patients were preoccupied by death. Additional follow-up findings are presented, and problems of diagnosis are discussed.
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Achte, K. A. Der Verlauf der Schizophrenien und der schizophreniformen Psychosen.Acta Psychiatrica et Neurologica Scandinavica Supplement 155, 1961,36, 1–273.
Andrews, E., & Cappon, D. Autism and schizophrenia in a child guidance clinic.Canadian Psychiatric Association Journal, 1957,2, 1–25.
Annell, L. A. The prognosis of psychotic syndromes in childhood.Acta Psychiatrica Scandinavica, 1963,39, 235–297.
Annesley, P. T. Psychiatric illness in adolescence: Presentation and prognosis.Journal of Mental Science, 1961,107, 268–278.
Bender, L. Childhood schizophrenia.Psychiatric Quarterly, 1953,27, 663–681.
Bender, L. The life course of schizophrenic children.Biological Psychiatry, 1970,2, 165–172.
Bender, L. The life course of children with schizophrenia.American Journal of Psychiatry, 1973,130, 783–786.
Bennett, S., & Klein, H. R. Childhood schizophrenia: 30 years later.American Journal of Psychiatry, 1966,122, 1121–1124.
Bleuler, E. Dementia praecox oder Gruppe der Schizophrenien. In G. Aschaffenburg (Ed.),Handbuch der psychiatrie, spezieller Teil, 4. Abtlg. Wien-Leipzig: Deuticke, 1911.
Boatman, M. J., & Szurek, S. A. A clinical study of childhood schizophrenia. In D. Jackson (Ed.),The etiology of schizophrenia. New York: Basic Books, 1960.
Chan, J. C. M., Fras, I., Wilson, M., & Moeller, H. G. Schizophrenia in infancy, childhood, and adolescence.American Journal of Diseases of Children, 1971,121, 538–542.
Clardy, E. R. A study of development and course of schizophrenia in children.Psychiatric Quarterly, 1951,25, 81–90.
Creak, M. Schizophrenia in early childhood.Acta Paedopsychiatrica, 1963,30, 42–47.
Creak, E. M., & Ini, S. Families of psychotic children.Journal of Child Psychology & Psychiatry & Allied Disciplines, 1960,1, 156–175.
De Sanctis, S.Neuropsichiatria infantile. Patologia e diagnostica. Turin: S. Lattes & Co., 1925.
Despert, L. Schizophrenia in children.Psychiatric Quarterly, 1938,12, 366–371.
Eaton, L., & Menolascino, F. J. Psychotic reactions of childhood: A follow-up study.American Journal of Orthopsychiatry, 1967,37, 521–529.
Eggers, C.Verlaufsweisen kindlicher und praepuberaler Schizophrenien. Monographien aus dem Gesamtgebiete der Psychiatrie. Psychiatry Series, Bd. 9. Berlin-Heidelberg-New York: Springer, 1973.
Eggers, C. Todesgedanken, Suicidversuche und Suicide im Verlauf kindlicher und präpuberaler Schizophrenien.Nervenarzt, 1974,45, 36–42.
Eisenberg, L. The course of childhood schizophrenia.A. M. A. Archives of Neurology and Psychiatry, 1957,78, 69–83.
Evensen, H. Dementia praecox. Aschehoug Krania 1904. Zit. n. G. Langfeldt. The prognosis in schizophrenia.Acta Psychiatrica et Neurologica Scandinavica Supplement 110, 1956, 7–66.
Fish, B. Contributions of developmental research to a theory of schizophrenia. In H. Hellmuth (Ed.),Exceptional infant (Vol. 2).Studies in abnormalities. New York: Brunner/Mazel, 1971.
Fish, B., Shapiro, T., Halpern, F., & Wile, R. The prediction ofschizophrenia in infancy.American Journal of Psychiatry, 1965,121, 768–775.
Gezlova, L. Einige Besonderheiten des Initialstadiums der Schizophrenie beim Kind im Vorschulalter.Zentralblatt für die Gesamte Neurologie und Psychiatrie, 1964,177, 294–295.
Gittelman, M. Introduction to M. Sh. Vrono.International Journal of Mental Health, 1976,5, 115.
Havelkova, M. Follow-up study of 71 children diagnosed as psychotic in preschool age.American Journal of Orthopsychiatry, 1968,38, 846–857.
Huber, G. Schizophrene Verläufe.Deutsche Medizinische Wochenschrift, 1964,89, 212–216.
Kanner, L. Autistic disturbances of affective contact.Nervous Child, 1943,2, 217–250.
Kanner, L. To what extent is early infantile autism determined by constitutional inadequacies?Association for Research in Nervous and Mental Disease, Proceedings, 1954,33, 378–385.
Kanner, L. Follow-up study of eleven autistic children originally reported in 1943.Journal of Autism and Childhood Schizophrenia, 1971,1, 119–145.
Kaufman, I., Frank, T., Friend, J. G., Heims, L. W., & Weiss, R. Adaptation of treatment techniques to a new classification of schizophrenic children.Journal of the American Academy of Child Psychiatry, 1963,2, 460–483.
Kemph, J. P. Psychotic children treated in a child guidance clinic.Diseases of the Nervous System, 1966,27, 317–320.
Kolvin, I. Studies in the childhood psychoses. I. Diagnostic criteria and classification.British Journal of Psychiatry, 1971,118, 381–384.
Kolvin, I. Research into childhood psychoses: A cross-cultural comparison and commentary.International Journal of Mental Health, 1974,2, 194–212.
Kolvin, I., Ounsted, C., Richardson, L. M., & Garside, R. F. Studies in the childhood psychoses. III. The family and social background in childhood psychoses.British Journal of Psychiatry, 1971,118, 396–402.
Langfeldt, G. The prognosis in schizophrenia.Acta Psychiatrica et Neurologica Scandinavica Supplement 110, 1956, 7–66.
Lebovici, S. Pronostic des névroses et des psychoses de l'enfant.Proceedings IV World Congress of Psychiatry, Madrid 1966. New York: Excerpta Medica. International Congress Series, No. 150, 1967.
Levy, S., & Southcombe, R. H. Value of convulsive therapy in juvenile schizophrenia.A. M. A. Archives of Neurology & Psychiatry, 1951,65, 54–59.
Lockyer, L., & Rutter, M. A five- to fifteen-year follow-up study of infantile psychosis. III. Psychological aspects.British Journal of Psychiatry, 1969,115, 865–882.
Lotter, V. Epidemiology of autistic conditions in young children.Social Psychiatry, 1966,1, 124–137.
Lotter, V. Factors related to outcome in autistic children.Journal of Autism and Childhood Schizophrenia, 1974,4, 263–277.
Mittler, P., Gillies, S., & Jukes, E. Prognosis in psychotic children.Journal of Mental Deficiency Research, 1966,10, 73–83.
Müller, M.Prognose und Therapie der Geisteskrankheiten. Stuttgart: Thieme, 1949.
Nameche, G., Waring, M., & Ricks, D. Early indicators of outcome in schizophrenia.Journal of Nervous and Mental Disease, 1964,139, 232–240.
Polonio, P. Periodic schizophrenia.Monatsschrift für Psychiatrie und Neurologie, 1954,128, 265–272.
Rees, S. C., & Taylor, A. Prognostic antecedents and outcome in a follow-up study of children with a diagnosis of childhood psychosis.Journal of Autism and Childhood Schizophrenia, 1975,5, 309–322.
Reiser, D. E. Psychoses of infancy and early childhood, as manifested by children with atypical development.New England Journal of Medicine, 1963,269, 790–798.
Rutter, M. The influence of organic and emotional factors on the origins, nature and outcome of childhood psychosis.Developmental Medicine and Child Neurology, 1965,7, 518–528.
Rutter, M. Prognosis: Psychotic children in adolescence and early adult life. In J. K. Wing (Ed.),Early childhood autism. London: Pergamon Press, 1966.
Rutter, M. Prognosis of infantile neuroses and psychoses.Proceedings of the IVth World Congress of Psychiatry, Madrid 1966. New York: Excerpta Medica. International Congress Series No. 150, 1967.
Rutter, M. Childhood schizophrenia reconsidered.Journal of Autism and Childhood Schizophrenia, 1972,2, 315–337.
Rutter, M. The development of infantile autism.Psychological Medicine, 1974,4, 147–163.
Rutter, M., & Lockyer, L. A five- to fifteen-year follow-up study of infantile psychosis. I. Description of sample.British Journal of Psychiatry, 1967,113, 1169–1182.
Sands, D. E. A special mental hospital unit for the treatment of psychosis and neurosis in juveniles.Journal of Mental Science, 1953,99, 123–129.
Spiel, W.Die endogenen Psychosen des Kindes- und Jugendalters. Basel-New York: Karger, 1961.
Ssucharewa, G. Über den Verlauf der Schizophrenien im Kindesalter.Zeitschrift für die Gesamte Neurologie und Psychiatrie, 1932,142, 309–321.
Ssucharewa, G. Die Bedeutung der vergleichenden Berücksichtigung des Lebensalters für die Untersuchung der Verlaufsgesetzmässigkeiten der Schizophrenie bei Kindern und Jugendlichen.Acta Paedopsychiatrica, 1967,34, 307–320.
Stutte, H. Die Prognose der Schizophrenien des Kindes- und Jugendalters.Congress Report of the IInd International Congress for Psychiatry, Zurich 1957 (Vol. I). Zurich: Orell Füssli, 1959.
Stutte, H. Kinder- und Jugendpsychiatrie. InPsychiatrie der Gegenwart, Bd. II. Berlin-Göttingen-Heidelberg: Springer, 1960.
Uschakov, G. K. Clinique de la schizophrénie.Psychiatrie de l'Enfant, 1965,8, 1–56.
Vrono, M. Sh. A reply to my opponents.International Journal of Mental Health, 1976,5, 115–125.
Wing, J. K. Five-year outcome in early schizophrenia.Proceedings of the Royal Society of Medicine, 1966,59, 17–18.
Wing, J. K. A standard form of psychiatric present state examination and a method for standardizing the classification of symptoms. In E. H. Hare & J. K. Wing (Eds.),Psychiatric epidemiology. Proceedings of the International Symposium held at Aberdeen University, July 1969. London: Oxford University Press, 1970.
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Eggers, C. Course and prognosis of childhood schizophrenia. J Autism Dev Disord 8, 21–36 (1978). https://doi.org/10.1007/BF01550275
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DOI: https://doi.org/10.1007/BF01550275