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Marsupial-mouse cell hybrids containing fragments of the marsupial X chromosome

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Somatic Cell Genetics

Abstract

Hybrids were obtained from fusions of HPRT-deficient mouse fibroblasts and marsupial lymphocytes. These hybrids retained no identifiable marsupial chromosomes, but all expressed the marsupial form of HPRT. Half the clones also expressed marsupial PGK-A, and half of these also marsupial G6PD; no other marsupial allozyme markers were detected. Since G6PD is known to be sex linked in these species, we conclude thatHpt andPgk-A are also located on the X chromosome and the markers lie in the orderHpt-Pgk-A-Gpd.

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Graves, J.A.M., Chew, G.K., Cooper, D.W. et al. Marsupial-mouse cell hybrids containing fragments of the marsupial X chromosome. Somat Cell Mol Genet 5, 481–489 (1979). https://doi.org/10.1007/BF01538882

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  • DOI: https://doi.org/10.1007/BF01538882

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