Skip to main content
SpringerLink
Log in

Long-term results of treatment of vascular malformations of the gastrointestinal tract by neodymium YAG laser photocoagulation

  • Original Articles
  • Published:
Digestive Diseases and Sciences Aims and scope Submit manuscript

Abstract

This study reports long-term results of treatment of vascular malformations of the gastrointestinal tract by neodymium YAG (Nd-YAG) laser photocoagulation in 60 patients (13 patients with hereditary hemorrhagic telangiectasia and 47 patients with angiodysplasias) and examines prognostic parameters of bleeding recurrence in 47 patients with angiodysplasias. In patients with hereditary hemorrhagic telangiectasia, the transfusion requirements were lower only in the second and third year following therapy than in the year before therapy; however, these differences were not significant. In patients with angiodysplasias, a median number of one laser session (range 1–8) was necessary to destroy angiodysplasias. A blood loss recurred in 15 patients. The cumulative probability of remaining free of blood loss recurrence at 24 months and at 54 months was 61±9%. Three parameters had an independent prognostic value, the initial number of angiodysplasias (P < 0.02), the presence of coagulation disorders (P < 0.05), and age (P < 0.05).

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Boley SJ, Brandt LJ: Vascular ectasias of the colon. Dig Dis Sci 31(suppl):26S-42S, 1986

    PubMed  Google Scholar 

  2. Weaver GA, Wilk HE, Olson JE: Successful endoscopic electrocoagulation of gastric lesions of hereditary hemorrhagic telangiectasia responsible for repeated hemorrhage. Gastrointest Endosc 27:181–183, 1981

    PubMed  Google Scholar 

  3. Weingart J, Elster K, Ottenjann R: Recurrent gastrointestinal bleeding in Osier's disease successfully treated by endoscopic electrocoagulation in the stomach. Endoscopy 7:160–164, 1975

    Google Scholar 

  4. Rutgeerts P, Van Gompel F, Geboes K, Vantrappen G, Broeckaert L, Coremans G: Long-term results of treatment of vascular malformations of the gastrointestinal tract by neodymium YAG laser photocoagulation. Gut 26:586–593, 1985

    PubMed  Google Scholar 

  5. Bown SG, Swain CP, Storey DW, Collins C, Matthewson K, Salmon PR, Clark CG: Endoscopic laser treatment of vascular anomalies of the upper gastrointestinal tract. Gut 26:1338–1348, 1985

    PubMed  Google Scholar 

  6. Rao CR: Linear Statistical Inference and its Application. New York, Wiley, 1973

    Google Scholar 

  7. Peto R, Pike MC, Armitage P: Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II. Analysis and examples. Br J Cancer 35:1–39, 1977

    PubMed  Google Scholar 

  8. Dixon WJ: BMDP Statistical Software. Los Angeles, University of California Press, 1987

    Google Scholar 

  9. Vase P, Grove O: Gastrointestinal lesions in hereditary hemorrhagic telangiectasia. Gastroenterology 91:1079–1083, 1986

    PubMed  Google Scholar 

  10. Rogers BHG, Adler F: Hemangiomas of the cecum. Colonoscopic diagnosis and therapy. Gastroenterology 71:1079–1082, 1976

    PubMed  Google Scholar 

  11. Howard OM, Buchanan JD, Hunt BM: Angiodysplasia of the colon. Lancet 2:16–19, 1982

    PubMed  Google Scholar 

  12. Jensen DM, Machicado GA, Silpa ML: Treatment of GI angioma with argon laser, heater probe or bipolar electrocoagulation. Gastrointest Endosc 30:134, 1984

    Google Scholar 

  13. Young W, Gilbert V, Feinstat T, Trudeau W: The recurrent upper gastrointestinal bleeding in hereditary hemorrhagic telangiectasia (Osier's disease) successfully treated by endoscopic sclerotherapy. Gastrointest Endosc 28:148, 1982

    Google Scholar 

  14. Bowers JH, Dixon JA: Argon laser photocoagulation of vascular malformations of the GI tract: Short-term results. Gastrointest Endosc 28:126, 1982

    Google Scholar 

  15. Sudry P, Brunetaud JM, Paris JC, Bretagne JF, Danielou Y, Bouret JF, Le Bodic MF, Le Bodic L: La photocoagulation par laser à argon des angiomes digestifs: à propos de quinze cas. Gastroenterol Clin Biol 5:426–432, 1981

    PubMed  Google Scholar 

  16. Waitman AM, Graut DZ, Chateau F: Argon laser photocoagulation treatment of patients with acute and chronic bleeding secondary to telangiectasia. Gastrointest Endosc 28:153, 1982

    Google Scholar 

  17. Maunoury V, Brunetaud JM, Cochelard D, Cortot A, Paris JC: Le traitement par laser des malformations vasculaires du tube digestif. Acta Endosc 18:73–80, 1988

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Service d'Hépato-Gastroentérologie, Hôpital Antoine Béclère, 157, rue de la Porte de Trivaux, 92141, Clamart Cedex, France

    S. Naveau, A. Aubert, T. Poynard & J. C. Chaput

Authors
  1. S. Naveau
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. A. Aubert
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. T. Poynard
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. J. C. Chaput
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Naveau, S., Aubert, A., Poynard, T. et al. Long-term results of treatment of vascular malformations of the gastrointestinal tract by neodymium YAG laser photocoagulation. Digest Dis Sci 35, 821–826 (1990). https://doi.org/10.1007/BF01536794

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01536794

Key words

Search

Navigation