Summary
Aqueous solutions of bile-acid salts give rise to a diffuse scattering of X-rays in the low-angle region, a phenomen that varies with the nature of the bile salt and with the concentration. The results of this study indicate the existence of micellar aggregates; these have a radius of about 20 Å in sodium desoxycholate solutions above 2.6% (0.065 molar) and about 17 Å in sodium cholate solutions above 3.7% (0.085 molar). With those radii the aggregation number would be 24 and 16, respectively. The aggregates in sodium dehydrocholate solutions appear not to reach colloid dimensions. Conjugation with taurin or glycine seems not significantly to change the structure of the colloid system.
Zusammenfassung
Wässerige Lösungen von Gallensäuresalzen zeigen eine diffuse Kleinwinkelstreuung, die mit der Natur der Gallensäuresalze und der Konzentration variiert. Aus den Untersuchungen folgt, daß mizellare Aggregate existieren müssen, deren Radius von ca. 20 Å in Nadesoxycholat-Lösungen über 2,6% (0,065 molar) und ca. 17 Å in Na-cholat-Lösungen über 3,7% (0,085 molar) beträgt. Bei diesen Durchmessern dürfte die Aggregationszahl 24 bzw. 16 betragen. Die Aggregate in Nadehydrocholat-Lösungen scheinen keine kolloidalen Dimensionen zu erreichen. Bei Konjugationen mit Taurin oder Glycin scheinen sich diese Strukturen nicht wesentlich zu ändern.
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