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Relativer Glutahion- und/oder Pyruvatkinasemangel in den Erythrocyten bei Panmyelopathien und akuten Leukämien

Relative deficiency of glutathione reductase and/or pyruvate kinase in erythrocytes in aplastic anemia and acute leukemia

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Summary

Relative deficiencies of glutathione reductase and/or pyruvate kinase were observed in the red cells of 10 of 11 patients showing various pancytopenias. Data obtained in the course of the disease suggest the presence of a secondary enzymatic abnormality which is without significance for the pathogenesis of the respective disorder.

Zusammenfassung

10 von 11 Patienten mit Panzytopenien verschiedener Genese hatten einen relativen Glutathionreductase-und/oder Pyruvatkinase-Mangel in den Erythrocyten. Die Verlaufsbeobachtung zeigte, daß es sich dabei um erworbene, transitorische Enzymdefekte, ohne pathogenetische Bedeutung für die Panzytopenie handelte.

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Literatur

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Authors and Affiliations

  1. Abteilung für Hämatologie und Gerinnungsforschung des Zentrums für innere Medizin und Kinderheilkunde der Universität Ulm, Germany

    U. R. Kleeberg, H. Heimpel, E. Kleihauer & Adelheid Olischläger

Authors
  1. U. R. Kleeberg
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  2. H. Heimpel
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  3. E. Kleihauer
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  4. Adelheid Olischläger
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Kleeberg, U.R., Heimpel, H., Kleihauer, E. et al. Relativer Glutahion- und/oder Pyruvatkinasemangel in den Erythrocyten bei Panmyelopathien und akuten Leukämien. Klin Wochenschr 49, 557–558 (1971). https://doi.org/10.1007/BF01487995

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  • DOI: https://doi.org/10.1007/BF01487995

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