Summary
Sera from 47 patients with sarcoidosis were examined for antibodies to Epstein-Barr virus, 63.8% of sarcoidosis patients were positive, against 74% of the clinical and 36% of the normal controls. The incidence of moderately elevated EBV-antibody titers in sarcoidosis patients was significantly (p<0.05) different from that in the controls. No significance, however, was found between sarcoidosis patients and clinical controls. It is concluded that the EB-virus does not play a major etiologic role in sarcoidosis. The slightly elevated EBV-antibody titers in sarcoidosis may rather be due to an increased humoral activity to certain antigens as described previously.
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Mit Unterstützung durch die Deutsche Forschungsgemeinschaft und das Landesamt für Forschung, Nordrhein-Westfalen.
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Becker, F.W., Gallmeier, W.M., Hertenstein, C. et al. Epstein-Barr-Virus- und lymphocytotoxische Serumantikörper in Sarkoidose-Patienten. Klin Wochenschr 50, 927–928 (1972). https://doi.org/10.1007/BF01487924
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DOI: https://doi.org/10.1007/BF01487924