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Beitrag zur vergleichenden Morphologie der epitheloiden Zellen der Nierenarteriolen unter besonderer Berücksichtigung der epitheloiden Zellen in den Nieren von Seewasserfischen

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Zusammenfassung

Vergleichende morphologische Untersuchungen zur Struktur der Nierenarteriolen, insbesondere der Vasa afferentia von Mensch, Maus und Seewasserfischen (Ordn. Elasmobranchii und Teleostei) hatten folgende Ergebnisse: 1. In den glomerulären und aglomerulären Nieren der aus acht verschiedenen Familien der Ordn. der Teleostier untersuchten Fische zeigen die Nierenarteriolen, im Gegensatz zur bisherigen Annahme, einen epitheloidzelligen Aufbau ihrer Media. Die e.Z. sind in glomerulären Teleostiernieren in Gefäßpolnähe häufig — wie oft in Säugernieren — in zwei bis drei Schichten in der Media angeordnet. 2. Die e.Z. der Teleostiernieren enthalten in ihrem Cytoplasma — wie die e.Z. der Mäuseniere — zahlreiche bei der PAS-Alzian-Blaufärbung leuchtend rote, versilberbare Granula. 3. In der Wand der Nierenarteriolen des zur Ordn. der Elasmobranchii gehörenden Acanthias vulgarisRisso sind e.Z. nicht vorhanden.

Die mögliche Funktion der e.Z. wird diskutier unter Hinweis auf die Tatsache, daß nicht nur in aglomerulären, sondern auch in glomerulären Teleostiernieren die bei Säugern bekannte Lagebeziehung zwischen e.Z. und Macula densa fehlt, da Seewasser-teleostier kein distales Tubulussegment besitzen.

Summary

Comparative morphological studies concerning the structure of renal arterioles, particularly the afferent arterioles in man, mouse and marine fishes (elasmobranchs and teleosts) led to the following results:

  1. 1.

    In contrast to former observations the renal arterioles of 8 different families of teleosts with glomerular or aglomerular kidneys proved to comprise within their walls epithelioid cells. As often seen in mammalian kidneys the epithelioid cells of glomerular teleost kidneys are frequently arranged in 2–3 layers within the media near the vascular pole.

  2. 2.

    Similar to mouse kidneys the epithelioid cells of teleosts contain within their cytoplasma numerous granules showing a bright purple colour, when stained by the PAS-Alcianblue procedure, and being representable by silver-impregnation.

  3. 3.

    There were no epithelioid cells within the walls of renal arterioles in Acanthias vulgarisRisso, belonging to the class Elasmobranchii.

The possible function of the epithelioid cells is being discussed refering to the fact that, contrarily to mammals, neither in aglomerular nor in glomerular kidneys of teleosts exists any topographical relation between epithelioid cells and macula densa, since the nephrons of marine teleosts have no distal tubular segment.

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Authors and Affiliations

  1. Aus dem Pathologischen Institut des Katharinenhospitals der Stadt Stuttgart, Germany

    A. Bohle, F. Walvig, Sigrun Helber & Anneliese Rauscher

  2. der Biologischen Station der Universität Oslo, Norway

    A. Bohle, F. Walvig, Sigrun Helber & Anneliese Rauscher

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  1. A. Bohle
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  2. F. Walvig
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  3. Sigrun Helber
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  4. Anneliese Rauscher
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Herrn Prof. Dr. Dr. h. c.Georg B. Gruber zum 80. Geburtstag gewidmet.

Mit Unterstützung der Deutschen Forschungsgemeinschaft.

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Bohle, A., Walvig, F., Helber, S. et al. Beitrag zur vergleichenden Morphologie der epitheloiden Zellen der Nierenarteriolen unter besonderer Berücksichtigung der epitheloiden Zellen in den Nieren von Seewasserfischen. Klin Wochenschr 42, 415–421 (1964). https://doi.org/10.1007/BF01486017

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