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Differenzierung von Pseudocholinesterase-Varianten im Diffusionstest

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Zusammenfassung

Es wird eine modifizierte Methode des „Diffusionstestes15 zur Bestimmung von Pseudocholinesterase-Varianten“ speziell zur Erfassung des atypischen Allels ChS und als Schnelltest für Familienuntersuchungen mitgeteilt. Der Vergleich mit spektrophotometrischen Aktivitäts- und Inhibitortesten zeigt, daß diese neue Methode für Routinemessungen besonders geeignet ist.

Summary

A modified method of the “screening test for the identification of the different pseudocholinesterase variants” is reported, which is specially suitable to identificate the atypical allele ChS and as a quick test for the investigation of families. A comparison with the spectrophotometrical test for enzyme activity and inhibitor constants shows, that this novel procedure is especially suitable in routinetests.

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Goedde, H.W., Fuss, W. Differenzierung von Pseudocholinesterase-Varianten im Diffusionstest. Klin Wochenschr 42, 286–289 (1964). https://doi.org/10.1007/BF01482376

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  • DOI: https://doi.org/10.1007/BF01482376

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