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Profil der Glucosestimulierten Insulinsekretion im Pfortaderblut des Menschen

Messungen in der frühen postoperativen Phase

Profil of the glucose-induced insulin secretion in human portal venous blood

Measurements in the early postoperative period

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Summary

The concentration of insulin in the portal venous blood shows in 8 patients in the early postoperative period under constant infusion of glucose a multiphasic course. The differences between the highest and lowest points are significant. Only the initial and the most prominent secondary peak can be followed up in the cubital venous blood. The role of the liver as buffer against the surplus of secreted insulin is discussed.

Zusammenfassung

Die Insulinkonzentration im Pfortaderblut bei 8 Patienten in der frühen postoperativen Phase zeigt unter konstanter Glucoseinfusion einen vielgipfligen Verlauf. Die Unterschiede zwischen Gipfel und Täler sind signifikant. Lediglich initialer und der am stärksten ausgeprägte sekundäre Gipfel sind auch im Cubitalvenenblut zu beobachten. Die Rolle der Leber als Puffer gegenüber überschüssig sezerniertem Insulin wird diskutiert.

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Authors and Affiliations

  1. Chirurgische Klinik im Klinikum Westend der Freien Universität Berlin, Germany

    R. Bittner, H. G. Beger & E. Kraas

Authors
  1. R. Bittner
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  2. H. G. Beger
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  3. E. Kraas
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Bittner, R., Beger, H.G. & Kraas, E. Profil der Glucosestimulierten Insulinsekretion im Pfortaderblut des Menschen. Klin Wochenschr 52, 575–577 (1974). https://doi.org/10.1007/BF01468499

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  • DOI: https://doi.org/10.1007/BF01468499

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