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Carcinoidsyndrom bei anaplastischem Pankreascarcinom

Carcinoidsyndrome due to anaplastic carcinoma of the pancreas

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Summary

A special case of a carcinoid syndrome is reported which differed from the regular type of this syndrome in two respects: 1. The overproduction of serotonin was due to a malignant carcinoma rather than to an ordinary carcinoid tumor. 2. The case was complicated by additional symptoms which would rather fit the Verner-Morrison syndrome. Considering the pertinent literature an attempt is made to differentiate between the symptomatology of the present type and that of the regular type of the carcinoid syndrome. Furthermore, the problems posed by the recognition and interpretation of the various symptoms resulting from the apparent coincidence of a Verner-Morrison syndrome with a carcinoid syndrome are discussed.

Zusammenfassung

Es wird über ein Carcinoidsyndrom berichtet, welches sich vom regulären Carcinoidsyndrom in zweierlei Hinsicht unterschied: 1. Die gesteigerte Serotoninproduktion ging nicht von einem Carcinoidtumor, sondern von einem Carcinom aus. 2. Es bestanden zusätzliche Symptome, die eher einem Verner-Morrison-Syndrom zuzuordnen waren. Anhand der Literatur wird versucht, die Symptomatik des vorliegenden von einem Carcinom ausgehenden Carcinoidsyndroms gegen die des regulären Carcinoidsyndroms abzugrenzen. Die Probleme bei der Erkennung und Deutung von Symptomen des Verner-Morrison-Syndroms bei gleichzeitig bestehendem Carcinoidsyndrom werden erörtert.

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Loewe, U., Höer, P.W. Carcinoidsyndrom bei anaplastischem Pankreascarcinom. Klin Wochenschr 52, 283–287 (1974). https://doi.org/10.1007/BF01468459

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