Summary
Somatosensory evoked potentials (SEP) and intracranial pressure (ICP) were studied in cats, suffering from a chronic spaceoccupying lesion produced by enlargement of an epidural balloon over the left sensomotory cortex. Our study shows that latency alterations of SEP are not dependent on the degree of ICP. Additionally, the results obtained demonstrate that chronic space-occupying lesions cause continuous prolongation of SEP latencies, probably produced by atrophy of the compressed tissue. Regarding the clinical importance of SEP measurements, we concluded that they are not suitable for estimating the degree of ICP. However, they are useful to evaluate tissue damage caused by mass effects in the acute and chronic phase of various space-occupying processes.
Similar content being viewed by others
References
Allison T, Hume A (1981) A comparative analysis of short latency somatosensory evoked potentials in man, monkey, cat, and rat. Exp Neurol 72: 592–611
Allison T, Wood CC, McCarthy G, Hume A, Goff WR (1982) Short latency somatosensory evoked potentials in man, monkey, cat, and rat: comparative latency analysis. In: Courjonet al (eds) Clinical applications of evoked potentials in neurology. Raven Press, New York
Bothe HW, Metzler G, Schürmann K (1992) A chronic spaceoccupying epidural lesion in cats as a tool to investigate masseffects of brain tumours. J Neurosurg: in preparation
DeSalles AF, Newlon PG, Katayama Y, Dixon CE, Becker DP, Stonington HH, Hayes RL (1987) Transient suppression of event-related evoked potentials produced by mild head injury in the cat. J Neurosurg 66: 102–108
Epstein F (1983) Increased ICP in hydrocephalic children with functioning shunts: a complication of shunt dependency. Concepts Pediatr Neurosurg 4: 119–130
Fujimoto S, Roccaforte P, Patel AR, Moody RA (1982) Intravascular aggregation after acute intracranial hypertension by epidural balloon compression in cats. J Neurosurg 57: 210–218
Gentili F, Longheed WM, Yamashiro K, Corrado C (1985) Monitoring of sensory evoked potentials during surgery of the skull base tumours. Can J Neurol Sci 12: 336–340
Goff GD, Matsumiya Y, Allison T, Goff WR (1977) The scalp topography of human somatosensory and auditory evoked potentials. Electroencephalogr Clin Neurophysiol 42: 57–76
Grossmann RG, Turner JW, Miller JD, Rowan JO (1973) The relationship between cortical electrical activity, cerebral perfusion pressure and cerebral blood flow during increased intracranial pressure. Stroke 4: 346
Grundy BL, Nelson PB, Doyle E, Procopio PT (1982) Intraoperative loss of somatosensory evoked potentials predict loss of spinal cord function. Anesthesiology 57: 321–322
Grundy BL, Heros RC, Tung AS, Doyle E (1981) Intra-operative hypoxia detected by evoked potential monitoring. Anesth Analg 60: 437–439
Handa Y, Hayashi M, Hirose S, Shirasaki N, Kobayashi H, Kawano H (1989) Changes of evoked potentials during pressure waves. In: Hoff JTet al (eds) Intracranial pressure, Vol 7. Springer, Berlin Heidelberg New York Tokyo, pp 238–240
Hekmatpanah J (1970) Cerebral circulation and perfusion in experimental increased intracranial pressure. J Neurosurg 32: 21–29
Iannotti F, Hoff JT, Schielke GP (1984) Brain tissue pressure: physiological observations in anaesthetized cats. J Neurosurg 60: 1219–1225
Iragui-Madoz VJ, Wiederholt WC (1977) Far-field somatosensory evoked potentials in the cat: correlation with depth recording. Am Neurol 1: 569–574
Koehler RC, Backofen JE, McPherson RW, Rogers MC, Traystman RJ (1986) Relationship of regional blood flow, evoked potential responses and systemic haemodynamics during intracranial hypertension. In: Miller JDet al (eds) Intracranial pressure, Vol 4. Springer, Berlin Heidelberg New York Tokyo, pp 365–368
Kuchiwaki H, Takada S, Misu N, Ishiguri H, Itoh J, Nagasaka M, Hirai N, Otha M, Kageyama N (1986) Studies of brain stem evoked potentials in relation to brain shifting during raised intracranial pressure induced by a frontal balloon and a temporal balloon. In: Miller JDet al (eds) Intracranial pressure, Vol 6. Springer, Berlin Heidelberg New York Tokyo, pp 339–344
Lienert GA (1973) Verteilungsfreie Methoden in der Biostatistik, Vol 1. Hain, Meisenheim, pp 212–263
Lorenz M, Gaab MR, Sollmann WP (1991) Somatosensory evoked potentials: diagnostic and prognostic value in head injuries. Adv Neurosurg 17: 97–101
Obeso JA (1980) Assessment of central conduction in somatosensory pathways. Electromyogr Clin Neurophysiol 20: 5–83
Raudzens PA, Shetter AG (1982) Intra-operative monitoring of brain stem auditory evoked potentials. J Neurosurg 57: 41–48
Reinoso-Suarez F (1961) Topographischer Hirnatlas der Katze für experimental-physiologische Untersuchungen. Merck, Darmstadt
Schramm J, Hashizume K, Fukushima T, Tekahashi H (1979) Experimental spinal cord injury produced by slow, graded compression. J Neurosurg 50: 48–57
Sutton LN, Cho B, Jaggi J, Joseph PM, Bruce DA (1986) Effects of hydrocephalus and increased intracranial pressure on auditory and somatosensory evoked responses. Neurosurgery 18: 756–761
Symon L, Wang AD, Costa e Silva IE, Gentili F (1984) Perioperative use of somatosensory evoked response in aneurysmal surgery. J Neurosurg 60: 269–275
Tsutsui T, Avila A, Symon L, Ono M, Wang A, Kalmanchey R (1986) The effects of a supratentorial mass lesion on brain stem auditory evoked potentials and short latency somatosensory evoked potentials. Neurol Res 8: 13–17
Wagner W (1988) Ableitung subkortikaler somatosensibel evozierter Potentiale mit Nasopharyngealelektroden — eine Untersuchung am sedierten Patienten. Z EEG-EMG 19: 141–147
Wang A, Cone J, Symon L, Costa E, Silva IE (1984) Somatosensory evoked potential monitoring during the management of aneurysmal SAH. J Neurosurg 60: 264–268
Williamson PD, Goff WR, Allison T (1970) Somatosensory evoked responses in patients with unilateral cerebral lesions. Electroencephalogr Clin Neurophysiol 28: 566–575
Witzmann A, (1988) Veränderungen somatosensorisch evozierter Potentiale bei kombinierter Anwendung von extra- und intrazerebralem Druck: eine experimentelle Studie. Z EEG-EMG 19: 133–140
Witzmann A, (1990) Changes of somatosensory evoked potentials with increase of intracranial pressure in the rat brain. Electroencephalogr Clin Neurophysiol 77: 59–67
Yamada T, Kimura J, Young S, Powers M (1978) Somatosensory evoked potentials elicited by bilateral stimulation of the median nerve and its clinical application. Neurology 28: 18–23
York DH, Pulliam MW, Rosenfeld JG, Watts C (1981) Relationship between visual evoked potentials and intracranial pressure. J Neurosurg 55: 909–916
Author information
Authors and Affiliations
Additional information
This work was supported in part by the Deutsche Forschungsgemeinschaft, grant Bo 920/1-2.
Rights and permissions
About this article
Cite this article
Bothe, H.W., Lee, S.W. & Samii, M. Somatosensory evoked potentials and intracranial pressure during chronic dilatation of an artificial extraparenchymal space-occupying lesion in cats. Acta neurochir 122, 105–112 (1993). https://doi.org/10.1007/BF01446995
Issue Date:
DOI: https://doi.org/10.1007/BF01446995