Summary
During an acute increase in ICP produced by balloon inflation three different phases could be observed. In the first phase (ICP 40–50 mm Hg) the latencies of R 1 and R 2 showed an initial decrease followed by increase in latency. In the second phase (ICP 50–70 mm Hg) R 2 disappeared, whereas R 1 showed marked alterations, prolongation of the latency and duration, and a decreasing amplitude. In the third phase no response could be evoked. The pathophysiological observations correlated with the morphological alterations. Two ischaemic zones with BBB damage which „transsected“ the mesodiencephalic and pontomesencephalic border were found. The results suggest that the disappearance of R 2 depends on rostral damage, whereas alteration of R 1 is caused by a pontomesencephalic lesion.
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This study was supported by Deutsche Forschungsgemeinschaft, SFB 32.
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Csécsei, G., Klug, N. & Rap, Z.M. Effect of increased intracranial pressure on the blink reflex in cats. Acta neurochir 68, 85–92 (1983). https://doi.org/10.1007/BF01406204
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DOI: https://doi.org/10.1007/BF01406204