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Radiologic-Pathologic Conference of Children's Hospital Boston: New pulmonary nodules in a child undergoing treatment for a solid malignancy

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Abstract

The appearance of pulmonary nodules in a child with a solid malignancy undergoing chemotherapy is a clinically worrisome event. The diagnosis in such cases is not always metastatic disease, and the differential diagnosis should include granulomatous disease, atelectasis, pneumonia, inflammatory pseudotumor, hamartoma, radiation pneumonitis, and bronchiolitis obliterans with organizing pneumonia. There is no consistent radiologic feature to help distinguish benign from malignant causes of these new lesions. However, repeat chest CT 4–6 weeks after the lesions are first noted can be used to track lesion progression and may obviate the need for biopsy.

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Author notes

  1. M. P. D'Alessandro

    Present address: Department of Radiology, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, 52242, Iowa City, IA, USA

Authors and Affiliations

  1. Department of Radiology, Children's Hospital and Harvard Medical School, Boston, Massachusetts, USA

    M. P. D'Alessandro & G. A. Taylor

  2. Department of Pathology, Children's Hospital and Harvard Medical School, Boston, Massachusetts, USA

    H. P. W. Kozakewich

  3. Department of Pediatric Oncology, Dana Faber Cancer Center, Boston, Massachusetts, USA

    K. R. Cooke

Authors
  1. M. P. D'Alessandro
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  2. H. P. W. Kozakewich
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  3. K. R. Cooke
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  4. G. A. Taylor
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D'Alessandro, M.P., Kozakewich, H.P.W., Cooke, K.R. et al. Radiologic-Pathologic Conference of Children's Hospital Boston: New pulmonary nodules in a child undergoing treatment for a solid malignancy. Pediatr Radiol 26, 19–21 (1996). https://doi.org/10.1007/BF01403697

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  • DOI: https://doi.org/10.1007/BF01403697

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