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Radiation-induced meningiomas and their proliferative activity

Cytokinetic study using bromodeoxyuridine

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Summary

Two cases of meningiomas, which are considered to have been caused by the preceding irradiation, are reported. In both cases, the cytokinetic study of the tumour using bromodeoxyuridine (BrdU) was performed. The percent of the tumour cells in the S phase of the cell cycle was less than 1% in both cases. The low labelling indices might suggest a relatively slow growing potential of these tumours, though the radiation-induced meningiomas were reported as being rapidly growing and malignant.

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Authors and Affiliations

  1. Department of Neurosurgery, Neurological Institute, Faculty of Medicine, Kyushu University, Fukuoka, Japan

    T. Tashima, M. Fukui, S. Nishio & K. Fujii

  2. Department of Neuropathology, Neurological Institute, Faculty of Medicine, Kyushu University, Fukuoka, Japan

    T. Iwaki

Authors
  1. T. Tashima
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  2. M. Fukui
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  3. S. Nishio
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  4. K. Fujii
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  5. T. Iwaki
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Tashima, T., Fukui, M., Nishio, S. et al. Radiation-induced meningiomas and their proliferative activity. Acta neurochir 102, 69–72 (1990). https://doi.org/10.1007/BF01402189

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