Skip to main content
Log in

Quantitative estimation of cholesterol in differentiating central nervous system of chick

  • Published:
Wilhelm Roux' Archiv für Entwicklungsmechanik der Organismen Aims and scope Submit manuscript

Summary

  1. 1.

    A quantitative estimation of cholesterol in the fore-, mid-, hindbrain and in spinal cord of the differentiating central system of chick has been made.

  2. 2.

    It is found that in the spinal cord area there is always a higher concentration of cholesterol than in the brain region.

  3. 3.

    Concentration of cholesterol increases upto 8 day of incubation and later it gradually decreases.

  4. 4.

    The reason for this differential synthesis of cholesterol has been discussed.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Allexander, J. G., andR. B. Allexander: Inhibition of cholesterol synthesis in vivo by a convulsant metrazol. Proc. Soc. exp. Biol. (N. Y.)115, 1, 229–232 (1964).

    Google Scholar 

  • Bloom, W., andD. A. Fawcett: A text book of histology, p. 239. London: W. B. Sanders Co. 1962.

    Google Scholar 

  • Bourne, G. H.: Microscopical localization of cholesterol in cells and tissues. In: Cholesterol (Ed.R. P. Cook), p. 349–374. New York: Academic Press 1957.

    Google Scholar 

  • Boyd, J. D.: Some aspect of the early development of the nervous system. In: Biochemistry of the developing nervous system (Ed.H. Waelsch), p. 3–27. New York: Academic Press 1955.

    Google Scholar 

  • BrÄchet, J.: Biochemistry of development. New York: Pergamon Press 1960.

    Google Scholar 

  • Clark, W. L. G.: In: Biochemistry of the developing nervous system (Ed.H. Waelsch), p. 25. New York: Academic Press 1955.

    Google Scholar 

  • Cook, R. P.: Distribution of sterols in organisms and tissues. In: Cholesterol (Ed.R. P. Cook), p. 145–180. New York: Academic Press 1957.

    Google Scholar 

  • Finean, J. B.: Phospholipid cholesterol complex in the structure of myelin. Experientia (Basel)9, 17–19 (1953).

    Google Scholar 

  • —: In: Biochemical problems of lipids (Ed.G. Popjak andE. Le Breton), p. 127–131. London: Butt, Pub. 1956.

    Google Scholar 

  • Floch-Pi, J.: Composition of the brain in relation to maturation. In: Biochemistry of developing nervous system (Ed.H. Waelsch), p. 121–136. New York: Academic Press 1955.

    Google Scholar 

  • Gould. R. G.: Biosynthesis of cholesterol. In: Cholesterol (Ed.R. P. Cook), p. 145–180. New York: Academic Press 1957.

    Google Scholar 

  • —, andR. P. Cook: The metabolism of cholesterol and other sterol in the animal organism. In: Cholesterol (Ed.R. P. Cook), p. 237–307. New York: Academic Press 1957.

    Google Scholar 

  • Hughes, A. F. W.: Ultraviolet studies on the developing nervous system of chick. In: Biochemistry of the developing nervous system (Ed.H. A. Waelsch), p. 166–176. New York: Academic Press 1955.

    Google Scholar 

  • Humberger, V.: Trends in experimental neuroembryology. In: Biochemistry of the developing nervous system (Ed.H. Waelsch), p. 52–73. New York: Academic Press 1955.

    Google Scholar 

  • Romanoff, A. L.: The avian embryos. New York: Mac & Co 1960.

    Google Scholar 

  • Roy, A. C., S. N. Dutta, andR. N. Sur: A rapid method for estimation of total adrenal cholesterol. J. Sci Ind. Research140, 124–125 (1955).

    Google Scholar 

  • Sere, P. A., I. L. Chaikoff, S. S. Treitman, andL. S. Burstein: The extra hepatic synthesis of cholesterol. J. biol. Chem.18, 629–634 (1950).

    Google Scholar 

  • Sperry, R. W.: Problems in biochemical specifications of neurons. In: Biochemistry of developing nervous system (Ed.H. Waelsch), p. 74–84. New York: Academic Press 1955.

    Google Scholar 

  • Waelach, H., W. M. Sperry, andV. A. Styanoff: Lipid metabolism in brain during myelinization. J. biol. Chem.135, 297–302 (1940).

    Google Scholar 

  • Weiss, P. A.: The problem of specificity in growth and development. Yale J. Biol. Med.19, 3, 235–278 (1947).

    Google Scholar 

  • —: Cell contact. Int. Rev. Cytol.7, 391–423 (1958).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Medda, J., Bose, A. Quantitative estimation of cholesterol in differentiating central nervous system of chick. W. Roux' Archiv f. Entwicklungsmechanik 157, 303–309 (1966). https://doi.org/10.1007/BF01342359

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01342359

Keywords

Navigation