Summary
Three epitopes which react with haemagglutination inhibition and neutralizing antibodies have been located between amino acids 245–285 in the predicted amino acid sequence of rubella envelope glycoprotein E1.
Similar content being viewed by others
References
Oker-Blom C (1984) The gene order for rubella virus structural proteins is NH2-C-E2-E1-COOH. J Virol 51: 354–358
Ho-Terry L, Cohen A (1980) Degradation of rubella virus envelope components. Arch Virol 65: 1–13
Dorsett PH, Miller DC, Green KY, Byrd FI (1985) Structure and function of the rubella virus proteins. Rev Infect Dis 7 [Suppl 1]: 150–156
Umino Y, Sato TA, Katow S, Matsuno T, Sugiura A (1985) Monoclonal antibodies directed to E1 glycoprotein of rubella virus. Arch Virol 83: 33–42
Waxham MN, Wolinski JS (1985) Detailed immunologic analysis of the structural polypeptides of rubella vius using monoclonal antibodies. Virology 143: 153–165
Ho-Terry L, Terry GM, Cohen A, Londesborough P (1986) Immunological characterisation of the rubella E1 glycoprotein. Arch Virol 90: 145–152
Vaheri A, Salonen E-M (1980) Evaluation of solid phase enzyme-immuno-procedure in immunity survey and diagnosis of rubella. J Med Virol 5: 171–181
Maizel JV Jr (1971) Polyacrylamide gel electrophoresis of viral proteins. In: Maramorosch K, Koprowski H (eds) Methods in virology, vol 5. Academic Press, New York, pp 180–246
Maniatis T, Fritsch EF, Sambrook J (1982) Molecular cloning. A laboratory manual. Cold Spring Harbour, New York
Okayama H, Berg P (1982) High-efficiency cloning of full-length cDNA. Mol Cell Biol 2: 161–170
Sanger F, Nicklen S, Coulson R (1977) DNA sequencing with chain terminating inhibitors. Proc Natl Acad Sci USA 74: 5463–5467
Niman HL, Elder JH (1982) Structural analysis of Rauscher Virus Gp70 using monoclonal antibodies: sites of antigenicity and P15(E) linkage. Virology 123: 187–205
Ho-Terry L, Cohen A (1984) The role of glycosylation on haemagglutination and immunological reactivity of rubella virus. Arch Virol 79: 139–146
Frey TK, Marr LD, Hemphill ML, Doninguez G (1986) Molecular cloning and sequencing of the region of the rubella virus genome coding for glycoprotein E1. Virology 154: 228–232
Oxford JS (1969) A comparison of some “wild” and “attenuated” strains of rubella virus. In: Regamey RH, Barbieri A, Hennssen W, Ikic D, Perkins FT (eds) International symposium on rubella vaccine. Karger, Basel New York, pp 181–186
Gould JJ, Butler M (1980) Differentiation of rubella virus strains by neutralization kinetics. J Gen Virol 49: 423–426
Ho-Terry L, Cohen A, Londesborough P (1982) Rubella sild-type and RA27/3 strains: a comparison by polyacrylamide gel electrophoresis and radioimmune precipitation. J Med Microbiol 15: 393–398
Best JM, Banatvala JE (1970) Studies on rubella virus strain variation by kinetic haemagglutination inhibition tests. J Gen Virol 9: 215–223
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Terry, G.M., Ho-Terry, L., Londesborough, P. et al. Localization of the rubella E1 epitopes. Archives of Virology 98, 189–197 (1988). https://doi.org/10.1007/BF01322168
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF01322168