Summary
Inoculation of invertebrate cells withChilo Iridescent Virus (CIV) leads rapidly to massive formation of syncytia. This polykaryocytosis occurs at a high multiplicity of infection and does not require viral genome expression. Thus, cell fusion appears in non permissive conditions, and CIV suspensions rendered non infections by UV irradiation still retain the ability to produce rapid and extensive cell fusion. In the same way, some polykaryocytes could be detected in vertebrate cells (CV1 cell line). However, this process is more effective and faster in invertebrate cell systems.
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Cerutti, M., Devauchelle, G. Cell fusion induced by an invertebrate virus. Archives of Virology 61, 149–155 (1979). https://doi.org/10.1007/BF01320599
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DOI: https://doi.org/10.1007/BF01320599