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The effect of preconceptional multivitamin supplementation on the menstrual cycle

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Abstract

The database of the Hungarian randomised controlled trial of periconceptional multivitamin supplementation for the prevention of neural-tube defects was used to evaluate the length of the pre- and postovulatory phases of the menstrual cycle before and during multivitamin supplementation. The female cycle was more regular (i.e., the variance was lower) during the multivitamin supplementation.

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References

  • Cohen HM (1973) Effects of Vitamin E: good and bad. N Engl J Med. 289:980–982

    Google Scholar 

  • Czeizel AE (1995) Folic acid in the prevention of neural tube defects. J Pediatr Gastroent Nutr 20:4–16

    Google Scholar 

  • Czeizel AE, Dudas I (1992) Prevention of the first occurrence of neural-tube defects by periconceptional vitamin supplementation. N Engl J Med 327:1832–1835

    Google Scholar 

  • Czeizel AE, Dudás I, Fritz G, Técsöi A, Hanck A, Kunovich G (1992) The effect of multivitamin/mineral supplementation on vertigo, nausea and vomiting in the first trimester of pregnancy. Arch Gynecol Obstet 251:181–185

    Google Scholar 

  • Czeizel AE, Dudás I, Métneki J (1994a) Pregnancy outcomes in a randomised controlled trial of periconceptional multivitamin supplementation. Arch Gynecol Obstet 255:131–139

    Google Scholar 

  • Czeizel AE, Métneki J, Dudás I (1994b) The effect of preconceptional multivitamin supplementation on fertility. Biol Reprod (submitted)

  • Czeizel AE, Métneki J, Dudás I (1994c) Higher rate of multiple births after periconceptional multivitamin supplementation. N Engl J Med 330:1687–1688

    Google Scholar 

  • Czeizel AE, Susánszky E (1994d) Diet intake and vitamin supplement use of Hungarian women during the preconceptional period. Internat J Vit Nutr Res 64:300–305

    Google Scholar 

  • Jameson S (1976) Effect of zinc deficiency in human reproduction. Acta Med Scand Suppl, p 593

  • Lindemann MD; Kornegay ET (1989) Folic acid supplementation to diets of gestating-lactating swine over multiple partities. J Anim Sci 67:459–464

    Google Scholar 

  • Matte JJ, Girard GL, Brisson GJ (1984) Folic acid and reproductive performance of sows. J Anim Sci 59:1020–1025

    Google Scholar 

  • MRC Vitamin Study Research Group (1991) Prevention of neural tube defects: results of the MRC vitamin study. Lancet 338:131–137

    Google Scholar 

  • Sanfilippo JS, Lyn YK (1991) Vitamin B deficiency and infertility: report of a case. Int J Fertil 36:36–88

    Google Scholar 

  • Smithells RW, Sheppard S, Schorah CJ, Seller MJ, Nevin NC, Harris R (1980) Possible prevention of neural tube defects by periconceptional vitamin supplementation. Lancet 1:339–340

    Google Scholar 

  • Smithells RW, Sheppard S, Wild J, Schorah CJ (1989) Prevention of neural tube defect recurrences in Yorkshire: Final report. Lancet 2:498–499

    Google Scholar 

  • Speroff L, Glass RH, Kase NG (1983) Clinical Gynecologic Endocrinology and Infertility. Williams and Wilkins, Baltimore

    Google Scholar 

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Dudás, I., Rockenbauer, M. & Czeizel, A.E. The effect of preconceptional multivitamin supplementation on the menstrual cycle. Arch Gynecol Obstet 256, 115–123 (1995). https://doi.org/10.1007/BF01314639

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  • DOI: https://doi.org/10.1007/BF01314639

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