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A comparison of Saint Louis encephalitis and Sindbis virus RNA

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Summary

RNA isolated from purified St. Louis encephalitis and Sindbis virus particles was compared by cellulose CF-11 chromatography, and RNase T1 and pancreatic RNase A digestion. SLE RNA eluted from the cellulose CF-11 column as a molecule with very little secondary structure, while Sindbis appears to have some internal bonding. Ribonuclease digestion indicates that SLE RNA contains 2.4 per cent polyadenylic acid.

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Brawner, T.A., Lee, J.C. & Trent, D.W. A comparison of Saint Louis encephalitis and Sindbis virus RNA. Archives of Virology 54, 147–151 (1977). https://doi.org/10.1007/BF01314387

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