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The effect of DNA hypomethylating agents on the reactivation of herpes simplex virus from latently infected mouse ganglia in vitro

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Summary

Effects of DNA hypomethylating agents on reactivation of herpes simplex virus from latently infected mouse ganglia in vitro were examined. L-ethionine and 5-azacytidine increased the incidence of reactivation. Dimethylsulphoxide and 5-azacytidine allowed earlier detection of virus.

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Authors and Affiliations

  1. Department of Microbiology, University of Bristol, Medical School, University Walk, Bristol, UK

    A. J. Whitby, W. A. Blyth & T. J. Hill

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  1. A. J. Whitby
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  2. W. A. Blyth
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  3. T. J. Hill
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Whitby, A.J., Blyth, W.A. & Hill, T.J. The effect of DNA hypomethylating agents on the reactivation of herpes simplex virus from latently infected mouse ganglia in vitro. Archives of Virology 97, 137–144 (1987). https://doi.org/10.1007/BF01310742

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  • DOI: https://doi.org/10.1007/BF01310742

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