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Amantadine inhibits an early, M 2 protein-dependent event in the replication cycle of avian influenza (H 7) viruses

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Summary

Analysis of the effects of amantadine during a single cycle of replication of A/FPV/Rostock virus in vitro showed that, as with other influenza A viruses, an M 2 protein-dependent step early in infection was inhibited. No effect was observed on later steps in replication under the conditions used.

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Author notes

  1. A. P. Kendal

    Present address: Influenza Branch, CDC, Atlanta, Georgia, USA

Authors and Affiliations

  1. Institute for Virology and Immunology, Philipps University, Marburg, Germany

    A. P. Kendal & H. D. Klenk

Authors
  1. A. P. Kendal
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  2. H. D. Klenk
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Kendal, A.P., Klenk, H.D. Amantadine inhibits an early, M 2 protein-dependent event in the replication cycle of avian influenza (H 7) viruses. Archives of Virology 119, 265–273 (1991). https://doi.org/10.1007/BF01310675

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  • DOI: https://doi.org/10.1007/BF01310675

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