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Thermal-pH inactivation of herpes simplex virus: Interdependence of the medium composition and the pH on the rate of virus inactivation

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Summary

The composition and pH of the suspending medium were shown to be interdependent effectors of thein vitro thermal inactivation of herpes simplex virus (HSV). In addition, enhanced thermal sensitivity of HSV at alkaline pH was a medium dependent effect and, therefore, is not an inherent property of the virus.

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References

  1. Ejercito, P., Kieff, E., Roizman, B.: Characterization of herpes simplex virus strains differing in their effect on social behavior of infected cells. J. gen. Virol.2, 357–364 (1968).

    Google Scholar 

  2. Figueroa, M., Rawls, W.: Biological markers for differentiation of herpes-virus strains of oral and genital origin. J. gen. Virol.4, 259–267 (1969).

    Google Scholar 

  3. Lancz, G.: Rapid method for the concentration and partial purification of herpes simplex virus types 1 and 2. Arch. ges. Virusforsch.42, 303–306 (1973).

    Google Scholar 

  4. Lancz, G.: Herpes simplex virus types 1 and 2: Type and strain specific characteristics affecting virus plaque formation. Arch. ges. Virusforsch.46, 36–43 (1974).

    Google Scholar 

  5. Lancz, G.: Effect of pH on the kinetics of herpes simplex virus inactivation at 36°. Virology75, 488–491 (1976).

    Google Scholar 

  6. Lancz, G.: Influence of environmental pH on the preservation and inactivation of herpes simplex virus. Proc. Soc. exp. Biol. Med.162, 238–240 (1979).

    Google Scholar 

  7. Plummer, G., Waner, J., Bowling, C.: Comparative studies of type 1 and 2 herpes simplex viruses. Brit. J. exp. Path.49, 202–208 (1968).

    Google Scholar 

  8. Smith, C., Lancz, G.: Abortive infection of neural cells by herpes simplex virus type 2. Arch. Virol.74, 311–323 (1982).

    Google Scholar 

  9. Smith, J., Rodriguez, J., McKee, A.: Biological characteristics of cloned populations of herpes simplex virus types 1 and 2. Appl. Microbiol.21, 350–357 (1971).

    Google Scholar 

  10. Wallis, C., Melnick, J.: Thermostabilization and thermosensitization of herpes virus. J. Bacteriol.90, 1632–1637 (1965).

    Google Scholar 

  11. Wigand, R., Bachmann, P., Brandner, G.: Stabilization of isometric DNA viruses against thermoinactivation by lowered ionic strength. Arch. Virol.69, 61–69 (1981).

    Google Scholar 

  12. Yanagi, K.: Irreversible conversion of the physical state of herpes simplex virus preceding inactivation by thermal or antibody treatment. J. Virol.38, 737–748 (1981).

    Google Scholar 

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Lancz, G., Sample, J. Thermal-pH inactivation of herpes simplex virus: Interdependence of the medium composition and the pH on the rate of virus inactivation. Archives of Virology 84, 141–146 (1985). https://doi.org/10.1007/BF01310561

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  • DOI: https://doi.org/10.1007/BF01310561

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