Summary
Monoclonal antibodies detect evident antigenic variations in NDV HN and F protein. However, the A/PMV-1 viruses can be identified by HI test using a preparation made of the combination of two different monoclonals.
A primary evaluation of the pathogenicity of the isolated viruses can be made by HI test using monoclonal antibodies but needs always confirmation using conventional pathogenicity tests.
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Meulemans, G., Gonze, M., Carlier, M.C. et al. Evaluation of the use of monoclonal antibodies to hemagglutinin and fusion glycoproteins of Newcastle disease virus for virus identification and strain differentiation purposes. Archives of Virology 92, 55–62 (1987). https://doi.org/10.1007/BF01310062
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DOI: https://doi.org/10.1007/BF01310062