Skip to main content
SpringerLink
Log in

A comparison of serological relationships among five ruminant alphaherpesviruses by ELISA

  • Brief Report
  • Published:
Archives of Virology Aims and scope Submit manuscript

Summary

Using enzyme-linked immunosorbent assays the cross reactivity of bovine herpesvirus-1.1, bovine herpesvirus-1.2, caprine herpesvirus-2, cervine (red deer) herpesvirus-1 and rangiferine (reindeer) herpesvirus-1 has been examined using rabbit hyperimmune antisera and convalescent cattle and red deer field sera. Significant cross-reactivity among all the five viruses was demonstrated. A detailed analysis showed that: (1) the two bovine herpesviruses are most closely related, (2) the cervine, caprine and rangiferine viruses are more closely related to the bovine viruses than they are to each other, (3) the cervine herpesvirus is more related to the bovine herpesvirus than to the rangiferine or caprine herpesviruses and (4) the rangiferine virus is more related to the cervine virus than to the bovine and caprine viruses. Cattle and red deer sera reacted most strongly with the bovine and cervine viruses respectively.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Ackermann M, Metzler AE, McDonagh H, Bruckner L, Muller HK, Kihm U (1986) Stellen nichtbovine Paarhufer ein IBR-Virus-Reservoir dar? I. BHV-1 und Cp HV-1 Infektions- and Reaktivierungsversuche an Ziegen, Virustypspezifität der humoralen Antikörper und Charakterisierung der viralen Antigene. Schweiz Arch Tierheilkd 128: 557–573

    Google Scholar 

  2. Archetti I, Horsfall FL (1950) Persistent antigenic variation of influenza A viruses after incomplete neutralization in ovo with heterologous immune serum. J Exp Med 92: 441–462

    Google Scholar 

  3. Berrios PE, McKercher DG, Knight HD (1975) Pathogenicity of a caprine herpesvirus. Am J Vet Res 36: 1763–1769

    Google Scholar 

  4. Brake F, Studdert MJ (1985) Molecular epidemiology and pathogenesis of ruminant herpesviruses including bovine buffalo and caprine herpesvirus 1 and bovine encephalitis herpesvirus. Aust Vet J 162: 331–334

    Google Scholar 

  5. Chow TL, Davis RW (1964) The susceptibility of mule deer to infectious bovine rhinotracheitis. Am J Vet Res 25: 518–519

    Google Scholar 

  6. Dawson PS, Darbyshire JH, Loosemore RM, Paterson AB, Faull WB (1962) Infectious bovine rhinotracheitis (IBR). A clinical condition of cattle occurring in the United Kingdom. Vet Rec 74: 1379–1383

    Google Scholar 

  7. Ek-Kommonen C, Veijalainen P, Rantala M, Neuvonen E (1982) Neutralising antibodies to bovine herpesvirus 1 in reindeer. Acta Vet Scand 23: 565–569

    Google Scholar 

  8. Ek-Kommonen C, Pelkonen S, Nettleton PF (1986) Isolation of a herpesvirus serologically related to bovine herpesvirus 1 from a reindeer (Rangifer tarandus). Acta Vet Scand 27: 299–301

    Google Scholar 

  9. El-Azhary S (1979) Serological edidence of IBR and BVD infection in caribou (Rangifer tarandus). Vet Rec 105: 336

    Google Scholar 

  10. Engels M, Gelderblom M, Darai G, Ludwig H (1983) Goat herpesvirus: biological and physicochemical properties. J Gen Virol 4: 2237–2247

    Google Scholar 

  11. Friedli K, Metzler AE (1987) Reactivity of monoclonal antibodies to proteins of a neurotropic bovine herpesvirus-1 (BHV-1) strain and to proteins of representative BHV-1 strains. Arch Virol 94: 109–122

    Google Scholar 

  12. Friend M, Halterman LG (1967) Serological survey of two herds in New York State. Bull Wildl Dis Assoc 3: 32–34

    Google Scholar 

  13. Hubalek Z (1982) Numerical comparative serology — the methods. J Appl Bacteriol 52: 307–318

    Google Scholar 

  14. Inglis DM, Bowie JM, Allan MJ, Nettleton PF (1983) Ocular disease in red deer calves associated with a herpesvirus infection. Vet Rec 113: 182–183

    Google Scholar 

  15. Lawman MJP, Evans D, Gibbs EPJ, McDiarmid A, Rowe L (1978) A preliminary survey of British deer for antibody to some virus diseases of farm animals. Br Vet J 134: 85–91

    Google Scholar 

  16. Lyaku JRS, Nettleton PF, Scott GR (1990) A quantitative enzyme-linked immunosorbent assay for bovine herpesvirus type 1 (BHV-1) antibody. Biologicals 18: 199–205

    Google Scholar 

  17. Martin WB, Castrucci G, Frigeri F, Ferrari M (1990) A serological comparison of some animal herpesviruses. Comp Immunol Microbiol Infect Dis 13: 75–84

    Google Scholar 

  18. Metzler F, Engels M, Wild P, Bivetti A (1979) Herpesvirus-Infektion bei Zicklein in der Schweiz. Schweiz Arch Tierheilkd 121: 665–661

    Google Scholar 

  19. Metzler F, Matile H, Gassmann U, Engels M, Wyler R (1985) European isolates of Bovine herpesvirus 1: a comparison of restriction endonuclease sites, polypeptides and reactivity with monoclonal antibodies. Arch Virol 85: 57–69

    Google Scholar 

  20. Nettleton PF, Herring JA, Sharp JM, Herring AJ, Dawson AMcL (1983) Comparison of an immunofluorescent test and an ELISA for the rapid diagnosis of infectious bovine rhinotracheitis in experimentally infected animals. Curr Top Vet Med Anim Sci 22: 132–141

    Google Scholar 

  21. Nettleton PF, Sharp JM (1980) Infectious bovine rhinotracheitis virus excretion after vaccination. Vet Rec 107: 379

    Google Scholar 

  22. Nettleton PF, Sinclair JA, Herring JA, Inglis DM, Fletcher TJ, Ross HM, Bonniwell MA (1986) Prevalence of herpesvirus infection in British red deer and investigation of further disease outbreaks. Vet Rec 118: 267–270

    Google Scholar 

  23. Nixon P, Edwards S, White H (1988) Serological comparisons of antigenically related herpesviruses in cattle, red deer and goats. Vet Res Commun 12: 355–362

    Google Scholar 

  24. Pastoret P-P, Thiry E, Brochier B, Schweirs A, Thomas I, Dubuisson J (1988) Diseases of wild animals transmissible to domestic animals. Rev Sci Techn Off Int Epizootiol 7: 705–736

    Google Scholar 

  25. Ronsholt L, Chistensen LS, Bitsch V (1987) Latent herpesvirus infection in red deer: characterization of a specific deer herpesvirus including comparison of genomic restriction fragment patterns. Acta Vet Scand 28: 23–31

    Google Scholar 

  26. St George TD, Philpott M (1972) Isolation of infectious bovine rhinotracheitis virus from the prepuce of water buffalo bulls in Australia. Aust Vet J 48: 126

    Google Scholar 

  27. Yates WDG (1982) A review of infectious bovine rhinotracheitis, shipping fever pneumonia and viral bacterial synergism in respiratory disease of cattle. Can J Comp Med 46: 225–263

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Moredun Research Institute, Edinburgh, Scotland

    J. R. S. Lyaku & P. F. Nettleton

  2. MRC Virology Unit, Institute of Virology, Glasgow, Scotland

    H. Marsden

Authors
  1. J. R. S. Lyaku
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. P. F. Nettleton
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. H. Marsden
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Lyaku, J.R.S., Nettleton, P.F. & Marsden, H. A comparison of serological relationships among five ruminant alphaherpesviruses by ELISA. Archives of Virology 124, 333–341 (1992). https://doi.org/10.1007/BF01309813

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01309813

Keywords

Search

Navigation