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Coat protein-mediated resistance in transgenic plants

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Summary

This review describes the proposed mechanism(s) of classical virus cross-protection in plants, followed by those suggested for coat protein-mediated resistance (CP-mediated resistance). Although both have common features, cross-protection is thought to be a complex response caused by the replication and expression of the entire viral genome, whereas the resistance conferred by the expression of a virus coat protein gene is more limited. The term genetically engineered cross-protection is frequently used because in many cases the phenotype of resistance mimics that of cross-protection. However, CP-mediated resistance, although a narrow term, more accurately describes the resistance that results from the expression of a virus CP gene in transgenic plants.

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Hackland, A.F., Rybicki, E.P. & Thomson, J.A. Coat protein-mediated resistance in transgenic plants. Archives of Virology 139, 1–22 (1994). https://doi.org/10.1007/BF01309451

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