Summary
Cytomegalovirus was isolated from chimpanzees. The chimpanzee CMV showed a strong antigenic relationship with human CMV. The genome of the chimpanzee CMV was found to have a molecular weight of 147±11.3×106 and showed partial homology to human CMV DNA.
References
Black, P. H., Hartley, J. W., Rowe, W. P.: Isolation of a cytomegalovirus from African green monkey. Proc. Soc. Exp. Biol. Med.112, 601–605 (1963).
Buitenwerf, J., de Jong, W., van Strien, A., van der Noordaa, J.: Characterization of SV40 transformed human liver cells before and after passage through crisis. Intervirology17, 222–227 (1982).
Geelen, J. L. M. C., Walig, C., Wertheim, P., van der Noordaa, J.: Human cytomegalovirus DNA I. Molecular weight and Infectivity. J. Virol.26, 813–816 (1978).
Griffin, B. E.: Structure and genomic organization of SV40 and Polymoavirus. In:Tooze, J. (ed.), DNA Tumor viruses (Molecular biology of tumor viruses, 2nd ed., Part 2), 61–123 (Cold Spring Harbour Monographs, 10 B). Cold Spring Harbour 1980.
Huang, E.-S., Kilpatrick, B., Lakeman, A., Alford, C. A.: Genetic analysis of a cytomegalovirus-like agent isolated from human brain. J. Virol.26, 718–723 (1978).
Huang, E.-S., Pagano, J. S.: Human cytomegalovirus. II. Lack of relatedness to DNA of herpes simplex I and II, Epstein-Barr virus and non-human strains of cytomegalovirus. J. Virol.13, 642–645 (1974).
Jeffreys, A. J., Flavell, R. A.: A physical map of the DNA regions flanking the rabbit beta-globin-gene. Cell12, 429–439 (1977).
Minamishima, Y., Graham, B. J., Benyesh-Melnik, M.: Neutralizing antibodies to cytomegalovirus in normal simian and human serum. Infect. Immun.4, 368–373 (1971).
Rigby, P. J., Dickman, M., Rhodes, C., Ber, P.: Labelling DNA to high specific activityin vitro by nick translation with DNA polymerase I. J. Mol. Biol.113, 237–251 (1977).
Southern, E. M.: Detection of specific sequences among DNA fragments separated by gel electrophoresis. J. Mol. Biol.98, 503–518 (1975).
Waner, J. L., Biano, S. A.: Antibody reactivity to human and vervet cytomegalovirus early antigen(s) in sera from patients with active cytomegalovirus infections and from asymptomatic donors. J. Clin. Microbiol.9, 134–140 (1979).
Weiner, D., Gibson, W.: Identification of a primate cytomegalovirus group-common protein antigen. Virology115, 182–191 (1981).
Wroblewska, Z., Gilden, D., Devlin, M., Huang, E.-S., Rorke, L. B., Hamada, T., Furukawa, T., Cummins, L., Katter, S., Koprowski, H.: Cytomegalovirus isolation from a chimpanzee with acute demyelinating disease after inoculation of multiple sclerosis brain cells. Infect. Immun.25, 1008–1015 (1979).
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Swinkels, B.W., Geelen, J.L.M.C., Wertheim-van Dillen, P. et al. Initial characterization of four cytomegalovirus strains isolated from chimpanzees. Archives of Virology 82, 125–128 (1984). https://doi.org/10.1007/BF01309376
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DOI: https://doi.org/10.1007/BF01309376