Abstract
The purpose of the present study is to show anomalies of the plasma cAMP response of patients with hepatic disorders to a single injection of a low dose of glucagon (1 μg/kg body wt). The response was markedly blunted in patients with liver cirrhosis and potentiated in patients with acute or chronic hepatitis. This glucagon test is, therefore, promising for development as a simple diagnostic means without undertaking liver biopsy to distinguish cirrhosis from chronic hepatitis.
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Maekubo, H., Matsushima, T., Okada, F. et al. Anomalous plasma cyclic AMP responses to glucagon in patients with liver disease. Digest Dis Sci 25, 700–704 (1980). https://doi.org/10.1007/BF01308330
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DOI: https://doi.org/10.1007/BF01308330