Summary
Consistent regression of intestinal metaplasia in Barrett's esophagus has not been achieved with medical or surgical interventions. In this case report, a patient with Barrett's esophagus of stable length had half the circumference of the Barrett's epithelium ablated with laser therapy while on a high-dose proton-pump inhibitor. In the absence of esophageal acid exposure and after laser ablation, the intestinal metaplasia was documented to reepithelialize with normal squamous mucosa, which has oersisted.
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Sampliner, R.E., Hixson, L.J., Fennerty, M.B. et al. Regression of Barrett's esophagus by laser ablation in an anacid environment. Digest Dis Sci 38, 365–368 (1993). https://doi.org/10.1007/BF01307557
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DOI: https://doi.org/10.1007/BF01307557