Skip to main content
SpringerLink
Log in

Relationship between functional and histological changes in chronic pancreatitis

  • Original Articles
  • Published:
Digestive Diseases and Sciences Aims and scope Submit manuscript

Abstract

The results of the secretin-CCK test were compared with the histological findings of pancreatic tissue resected in 25 patients with chronic pancreatitis. Secretin-CCK test results were interpreted with the use of discriminant analysis, yielding a quantitative score for each patient. Histological findings were recorded according to a semiquantitative scale. Fairly high correlation coefficients were found between secretin-CCK test results and severity of acinar atrophy and small dilatation. These findings emphasize the importance of the secretin-CCK test for diagnostic and follow-up purposes in chronic pancreatitis.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Vennes JA: Editorial: Chronic pancreatitis. Gastroenterology 82:1471–1472, 1982

    Google Scholar 

  2. Heij HA, Obertop H, Schmitz PIM, van Blankenstein M, Westbroek DL: Evaluation of the secretin-CCK test for chronic pancreatitis using discriminant analysis. Scand J Gastroenterol 21:35–40, 1986

    Google Scholar 

  3. Nakamura K, Sarles H, Payan H: Three dimensional reconstruction of the pancreatic ducts in chronic pancreatitis. Gastroenterology 62:942–949, 1972

    Google Scholar 

  4. Sarles H, Sahel J: Pathology of chronic calcifying pancreatitis. Am J Gastroenterol 66:117, 1976

    Google Scholar 

  5. Sarles H, Sahel J, Palasciano G, Capitaine Y, Meullenet J: Alcohol consumption and the human pancreas.In Alcohol and the GI Tract. C Stock, JC Bode, H Sarles (eds). Inserm, Paris, 1980, pp 289–314

    Google Scholar 

  6. Gebhardt C, Gall FP, Mühe E, Lauterwald A: Ist die totale Pankreatektomie zur Behandlung der chronischen Pankreatitis noch zu verantworten? Langenbecks Arch Chir 350:129–137, 1979

    Google Scholar 

  7. Adler M, Waye JD, Dreiling DA: The pancreas, a correlation of function, structure and histopathology. Acta Gastroenterol Belg 39:502, 1976

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Surgery, Dijkzigt University Hospital, Erasmus University, Dr. Molewaterplein 40, 3015 GD, Rotterdam, Netherlands

    H. A. Heij MD, H. Obertop MD, M. van Blankenstein MD, F. W. ten Kate MD & D. L. Westbroek MD

  2. Department of Gastroenterology, Dijkzigt University Hospital, Erasmus University, Rotterdam, Netherlands

    H. A. Heij MD, H. Obertop MD, M. van Blankenstein MD, F. W. ten Kate MD & D. L. Westbroek MD

  3. Department of Pathology, Dijkzigt University Hospital, Erasmus University, Rotterdam, Netherlands

    H. A. Heij MD, H. Obertop MD, M. van Blankenstein MD, F. W. ten Kate MD & D. L. Westbroek MD

Authors
  1. H. A. Heij MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. H. Obertop MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. M. van Blankenstein MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. F. W. ten Kate MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. D. L. Westbroek MD
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Heij, H.A., Obertop, H., van Blankenstein, M. et al. Relationship between functional and histological changes in chronic pancreatitis. Digest Dis Sci 31, 1009–1013 (1986). https://doi.org/10.1007/BF01300251

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01300251

Keywords

Search

Navigation