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Gastritic glandularis et cystica profunda

A report of three cases with discussion of etiology and pathogenesis

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Abstract

Three cases of gastritis glandularis et cystica profunda are presented, two associated with severe chronic gastritis and the other with invasive gastric carcinoma and chronic gastritis. This poorly known entity consists of benign downgrowths of deep gastric glands through the muscularis mucosae into, the submucosa. The pattern is primarily adenomatous with secondary cyst formation, which varies in extent and severity. The lesion is related to the chronic gastritis but why it should occur so rarely in such a common condition as chronic gastritis remains obscure. More documented cases are needed before a meaningful analysis can be attempted.

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References

  1. Wayte DM, Helwig EB: Colitis cystica profunda. Am J Clin Pathol 48:159–169, 1967

    Google Scholar 

  2. Baillie EE, Abell MR: Enteritis cystica profunda. Am J Clin Pathol 54:643–649, 1970

    Google Scholar 

  3. Scotti TM: Simian gastropathy with submucosal glands and cysts. Arch Pathol 96:403–408, 1973

    Google Scholar 

  4. Stewart MJ, Taylor AL: Adenomyoma of stomach. J Pathol Bact 28:195–202, 1925

    Google Scholar 

  5. Clarke BE: Myoepithelial hamartoma of the gastrointestinal tract. Arch Pathol 30:143–152, 1940

    Google Scholar 

  6. Scott WH Jr, Payne TPB: Diffuse congenital, cystic hyperplasia of stomach clinically stimulating carcinoma. Bull Johns Hopkins Hosp 81:448–455, 1947

    Google Scholar 

  7. Oberman HA, Lodmell JG, Sower ND: Diffuse heterotopic cystic malformation of stomach. N Engl J Med 269:909–911, 1963

    Google Scholar 

  8. Sussman HM, Weingarten B, Missberg SM: Localized gastric mucosal hypertrophy simulating tumor. Am J Dig Dis 10:710–718, 1965

    Google Scholar 

  9. Iwanaga T, Koyama H, Takahasi Y, et al: Diffuse submucosal cysts and carcinoma of the stomach. Cancer 36:606–614, 1975

    Google Scholar 

  10. Lipper S, Kahn LB: Superficial cystic gastritis with alopecia. A forme fruste of the Cronkite-Canada syndrome. Arch Pathol Lab Med 101:432–436, 1977

    Google Scholar 

  11. Butz WC: Giant hypertrophic gastritis: A report of fourteen cases. Gastroenterology 39:183–190, 1960

    Google Scholar 

  12. Litter ER, Gleberman E: Gastritis cystica polyposa (gastric mucosal prolapse at gastroenterostomy site, with cystic and infiltrating epithelial hyperplasia). Cancer 29:205–209, 1972

    Google Scholar 

  13. Griffel B, Engelberg M, Reiss R, et al: Multiple polypoid cystic gastritis in old gastroenteric stroma. Arch Pathol 97:316–318, 1974

    Google Scholar 

  14. Allen JR, Norback DG: Polychlorinated biphenyl-and triphenyl-induced gastric mucosal hyperplasia in primates. Science 179:498–499, 1973

    Google Scholar 

  15. Brynjolfsson, G, Haley HB: Experimental enteritis cystica in rats. Am J Clin Pathol 47:69–73, 1967

    Google Scholar 

  16. Brynjolfsson G, Lombardi S: Colitis cystica in mice. Cancer 23:226–229, 1969

    Google Scholar 

  17. Glass GBJ, Pitchumon CS: Atrophic gastritis. Hum Pathol 6:219–250, 1975

    Google Scholar 

  18. The Newfoundland Cancer Treatment and Research Foundation Annual Report: Fig 3, p 16, 1976–1977

  19. Meikle DD, Taylor KB, Truelove SC, et al: Gastritis, duodenitis and circulating levels of gastrin in duodenal ulcer before and after vagotomy. Gut 17:719–728, 1976

    Google Scholar 

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Honoré, L.H., Lewis, A.S. & O'Hara, K.E. Gastritic glandularis et cystica profunda. Digest Dis Sci 24, 48–52 (1979). https://doi.org/10.1007/BF01297238

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  • DOI: https://doi.org/10.1007/BF01297238

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