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Biological characteristics of rubella virus as assayed in a human amnion culture system

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Summary

We have briefly reviewed observations stemming from the finding that rubella virus may be grown in cultures of human amnion cells with the production of specific cytopathic changes. Rubella research is now in a phase of rapid development. While it is hoped that the information accumulated to date will not in the future be proven erroneous, it can be confidently predicted that the somewhat laborious and poorly standardized methodology now available for the investigation of rubella virus will undergo rapid refinement and simplification. Rubella will then move from the province of the research bench to the routine diagnostic laboratory.

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Authors and Affiliations

  1. Department of Tropical Public Health, Harvard School of Public Health, Boston, Massachusetts, USA

    Thomas H. Weller (Richard Pearson Strong Professor of Tropical Public Health and Chairman) & Franklin A. Neva (Professor of Tropical Public Health, Harvard School of Public Health)

  2. Department of Tropical Public Health, Harvard School of Public Health, USA

    Thomas H. Weller (Richard Pearson Strong Professor of Tropical Public Health and Chairman) & Franklin A. Neva (Professor of Tropical Public Health, Harvard School of Public Health)

Authors
  1. Thomas H. Weller
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  2. Franklin A. Neva
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Additional information

Supported in part by a research grant (AI-01023) from the National Institute of Allergy and Infectious Diseases, National Institutes of Health, United States Public Health Service, and by grants from Parke, Davis and Company and United Cerebral Palsy Research and Educational Foundation, Incorporated.

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Weller, T.H., Neva, F.A. Biological characteristics of rubella virus as assayed in a human amnion culture system. Archiv f Virusforschung 16, 393–400 (1965). https://doi.org/10.1007/BF01253845

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  • DOI: https://doi.org/10.1007/BF01253845

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