Summary
The cholinergic innervation of the dura mater in the guinea pig, mouse and rat has been investigated.
The dura mater is provided with a cholinergic innervation. After short incubation times (4–6 hours) we found acetylcholinesterase (AChE)-containing nerve fibers in close relationship with the main meningeal blood vessels. After longer incubation times, AChE-containing nerve fibers appear also in the meningeal tissue proper.
Chemical sympathectomy, performed with the neurotoxin 6-hydroxydopamine, does not seem to interfere with the pattern of the dural cholinergic innervation. The findings are discussed.
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Amenta, F., Sancesario, G., Ferrante, F. et al. Acetylcholinesterase-containing nerve fibers in the dura mater of guinea pig, mouse, and rat. J. Neural Transmission 47, 237–242 (1980). https://doi.org/10.1007/BF01250604
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DOI: https://doi.org/10.1007/BF01250604