Summary
Some properties of the little known Israel turkey virus which causes annual epidemics among flocks of turkeys have been investigated. Suckling mice were susceptible to intracerebral, intraperitoneal, subcutaneous and intranasal inoculation of the virus while young adult mice died only after intracerebral and intranasal administration of the virus. Suckling hamsters were susceptible to intracerebral inoculation.
The virus was sensitive to ether and deoxycholate treatment. It was found to be fairly stable at low temperatures. Filtration experiments through Millipore filters point to a virion size between 100 mμ. and 50 mμ. An antigen prepared by the sucrose-acetone method agglutinated erythrocytes of a wide range of vertebrate species, optimal pH being 6.2–6.6. Attempts were made to grow the virus in many cell systems. Plaques were consistently obtained in chick embryo fibroblast cultures. Transmission of virus from laboratory fed mosquitoes to suckling mice was successfully carried out.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Andrewes, C. H., andD. M. Horstmann: The susceptibility of viruses to ethyl ether. J. gen. Microbiol.3, 290 (1949).
Casals, J.: Filtration of arboviruses through Millipore membranes. Nature (Lond.)217, 648–649 (1968).
Clarke, D. H., andJ. Casals: Techniques for hemagglutination and hemagglutination-inhibition with arthropod-borne viruses. Amer. J. Hyg.7, 561–573 (1958).
Haldane, J. B. S.: “De” or “Order of magnitude”? Nature (Lond.)187, 879 (1960).
Kissling, R. E., D. D. Stamm, R. W. Chamberlain, andW. D. Sudia: Birds as winter hosts for eastern and western equine encephalomyelitis viruses. Amer. J. Hyg.66, 42–47 (1957).
Komarov, A., andE. Kalmar: A hitherto underscribed disease-turkey meningoencephalitis. Vet. Rec.72, 257–261 (1960).
Mussgay, M.: Growth cycle of arboviruses in vertebrate and arthropod cells. Progr. med. Virol.6, 193–267 (1964).
Negroni, G.: Tissue culture techniques. In: Techniques in experimental Virology (R. J. C. Harris, ed.), pp. 327–358, London: Academic Press, 1964.
Nie, Y.: Preparation of an infectious ribonucleic acid derived from mouse brains infected with Israel turkey meningo-encephalitis virus. Arch. ges. Virusforsch.29, 215–221 (1970).
Nir, Y., R. Goldwasser, Y. Lasowski, andJ. Margalit: Isolation of West Nile virus strains from mosquitoes in Israel. Amer. J. Epidem.87, 496–501 (1968).
Peleg (Kaplansky), B. A.: A small-scale serological survey of Israel turkey meningo-encephalitis (ITME). Refuah vet.20, 250–253 (1963).
Porterfield, J. S.: Israel turkey meningo-encephalitis virus. Vet. Rec.73, 302–394 (1961).
Reed, L. J., andH. Muench: A simple method of estimating fifty per cent endpoints. Amer. J. Hyg.27, 493–497 (1938).
Sever, J. L.: Application of a microtechnique to viral serological investigations. J. Immunol.88, 320–329 (1962).
Tauraso, N. M., andA. Shelokov: Arboviruses -A problem in classification. Arch. ges. Virusforsch.22, 273–279 (1967).
Theiler, M.: Action of sodium desoxycholate on arthropod-borne viruses. Proc. Soc. exp. Biol. (N.Y.)96, 380–382 (1959).
Wld Hlth Org. Scientific Group: Arboviruses and human disease. Wld Hlth Org. techn. Rep. Ser., No. 369 (1967).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Nir, Y. Some characteristics of Israel turkey virus. Archiv f Virusforschung 36, 105–114 (1972). https://doi.org/10.1007/BF01250300
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF01250300