Summary
Dopamine receptors were localized autoradiographically in the rat spinal cord afterin vitro labelling using3H-N-propylnorapomorphine (NPA). The highest densities of3H-NPA binding sites were found in the substantia gelatinosa and in a zone of the grey matter immediately ventral to the dorsal corticospinal tract. Other areas of the grey matter presented only moderate or low receptor densities while no3H-NPA binding sites could be found in the white matter. The localization of3H-NPA binding sites is compatible with a role for spinal cord dopamine in the processing of sensory information.
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Scatton, B., Dubois, A. & Cudennec, A. Autoradiographic localization of dopamine receptors in the spinal cord of the rat using [3H]-N-propylnorapomorphine. J. Neural Transmission 59, 251–256 (1984). https://doi.org/10.1007/BF01250012
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DOI: https://doi.org/10.1007/BF01250012