Summary
Three different approaches of freezing rabbit tibia bones are demonstrated. Intramedullary freezing seems to be the safest method to avoid soft tissue necrosis. Bone specimens removed immediately after the freezing-thawing process showed electron optically evidence of irreversible damage of bone cells in all cases.
Zusammenfassung
Die verschiedenen Methoden der Frierung von Tibiaknochen des Kaninchens werden beschrieben. Davon zeigt die intrameditlläre Methode die geringsten Nebenwirkungen. In jedem Fall konnten elektronenoptisch sofort nach dem Frier-Tau-Vorgang Zeichen der irreversiblen Schädigung von Knochenzellen beobachtet werden.
Similar content being viewed by others
References
Gage, A., Green, G., Neiders, M., Emmings, F.: Freezing bone without excision. J. Am. Med. Ass.196, Nr.9 (1966)
Marcove, R., Lyden, J., Huvos, A., Bullough, P.: Giant-cell tumors treated by cryosurgery. J. Bone Jt. Surg.55-A, Nr. 8 (1973)
Marcove, R. C., Stovell, P. B., Huvos, A. G., Bullough, P. G.: The use of cryosurgery in the treatment of low and medium grade chondrosarcoma. Clin. Orth. Rel. Res.122, 147 (1977)
Mazur, P.: Causes of injury in frozen and thawed cells. Fed. Proc.24, 175–182 (1965)
Smith, A. U.: Biological effects of freezing and supercooling. Monographs of the Physiological Society, Nr. 9. Baltimore: Williams and Wilkins 1961
Author information
Authors and Affiliations
Additional information
Dedicated Prof. Dr. E. Uehlinger on his 80th birthday
Rights and permissions
About this article
Cite this article
Kerschbaumer, F., Russe, W., Weiser, G. et al. Cryolesions of bone. Arch. Orth. Traum. Surg. 96, 5–9 (1980). https://doi.org/10.1007/BF01246134
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF01246134