Summary
Colonies of hamster embryo cells transformed by adenovirus type 12 are characterized by, among other things, the tight packing of small polygonal cells. These cells react selectively with DNA specific reagents. Counting of colonies after reaction with Feulgen or Toluidine blue was possible with the naked eye, and gave counts superior to those in unstained condition under the microscope.
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This work was supported by the National Institutes of Health, National Institute of Allergy and Infectious Diseases (Contract PH 43-62-200) and the National Cancer Institute (Contract PH 43-64-941).
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Schell, K., Schmidt, M. Adenovirus transformation of hamster embryo cells. Archiv f Virusforschung 24, 332–341 (1968). https://doi.org/10.1007/BF01243074
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DOI: https://doi.org/10.1007/BF01243074