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Possible antigenic relationship between varicella/ zoster virus and herpes simplex virus

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Summary

Cultures of the “Gabi” strain of diploid cells derived from human fetal lung fibroblasts were used for isolation of virus from typical cases of varicella and herpes zoster. CF antigens were prepared from 2 varicella and 2 zoster strains. Similar antibody responses to these antigens were demonstrated in paired sera from the four patients who provided the virus strains and one other case of herpes zoster. None of these sera reacted with herpes simplex antigen.

Out of 49 patients with a significant rise of CF antibody titer against herpes simplex virus, 12 had a similar response against varicella antigen. These findings suggest a minor antigenic relationship between both viruses.

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Authors and Affiliations

  1. National Institute of Public Health, Utrecht, The Netherlands

    Jacoba G. Kapsenberg

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  1. Jacoba G. Kapsenberg
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Kapsenberg, J.G. Possible antigenic relationship between varicella/ zoster virus and herpes simplex virus. Archiv f Virusforschung 15, 67–73 (1964). https://doi.org/10.1007/BF01241422

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  • DOI: https://doi.org/10.1007/BF01241422

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