Skip to main content
SpringerLink
Log in

Studies on the biological characteristics of the newcastle disease virus (NDV) adapted to the brain of newborne mice

  • Published:
Archiv für die gesamte Virusforschung Aims and scope Submit manuscript

Summary

A Hungarian strain of NDV proved to be very easily adaptable to the brain of newborne mice. The adapted virus was unable for growth in the brain of adult mice, showed enhanced carcinostatic activity and diminished pathogenicity for young chickens. It was easily neutralizable by anti-NDV immune sera. In the postembryonal mouse brain previously inoculated with egg line virus, the growth of the mouse adapted virus was significantly hindered by interference.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Literature

  1. Burnet, F. M.: Austral. J. exper. Med. Sci20, 81 (1942).

    Google Scholar 

  2. Ginsberg, H.S.: J. exper. Med. (Am.)94, 191 (1951).

    Google Scholar 

  3. Davenport, F. M.: J. Im-munol. (Am.)69, 461 (1952).

    Google Scholar 

  4. Sinkovics, J.: Magy. Allatorv. L.23, 24 (1949).

    Google Scholar 

  5. Hallauer, C. andG. Kronauer: Arch. ges. Virusforsch.5, 441 (1954).

    PubMed  Google Scholar 

  6. Brandly, C. A., H. E. Moses, E. L. Jungherr, andE. E. Jones: Amer. J. Vet. Res.7, 289 (1946).

    Google Scholar 

  7. Upton, E., R. P. Hanson, D. Dow, andC. Abrandly: J. Inf. Dis.92, 175 (1953).

    Google Scholar 

  8. Kilham, L., L. L. Loomis, andJ. Hpeers: Amer J. Vet. Res.46, 95 (1952).

    Google Scholar 

  9. Flanagan, A. D., R. Love, and.W. Tesar: Proc. Soc. exper. Biol. a. Med. (Am.)90, 82 (1955).

    Google Scholar 

  10. Moore A.E., andL. C. Diamond: J. Immunol. (Am.)77, 81 (1956).

    Google Scholar 

  11. Kilham, L.: Proc. Soc. exper. Biol. a. Med. (Am.)74, 220 (1950).

    Google Scholar 

  12. Kitayama, T., S. Sunakowa, andH. Fukumi: Jap. J. Med. Sci. Biol.6, 405 (1953).

    PubMed  Google Scholar 

  13. Upton, E., R. P. Hanson, D. Dow, andC. A. Brandly: J. Inf. Dis.96, 24 (1955).

    Google Scholar 

  14. Upton, E., R. P. Hanson, andC. A. Brandly: J. Inf. Dis.96, 29 (1955).

    Google Scholar 

  15. Groupé, V., andR. M. Dougherty: J. Immunol. (Am.)76, 130 (1956).

    Google Scholar 

  16. Sinkovics, J.: Archiv ges. Virusforsch.7, 242 (1957).

    Google Scholar 

  17. Reed, L. J., andH. Muench: Amer. J. Hyg.27, 493 (1938).

    Google Scholar 

  18. Hirst,G. K.: J. exper. Med. (Am.)86, 357 (1947).

    Google Scholar 

  19. Ginsberg, H. S., andF. Lhorsfall, Jr.: J. exper. Med.89, 37 (1949).

    Google Scholar 

Download references

Author information

Author notes

  1. J. Sinkovics M. D.

    Present address: Institute of Microbiology Rutgers, The State University of New Jersey, New Brunswick, N. J., USA

Authors and Affiliations

  1. State Institute of Hygiene, Budapest

    J. Sinkovics M. D.

Authors
  1. J. Sinkovics M. D.
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Sinkovics, J. Studies on the biological characteristics of the newcastle disease virus (NDV) adapted to the brain of newborne mice. Archiv f Virusforschung 7, 403–411 (1957). https://doi.org/10.1007/BF01240748

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01240748

Keywords

Search

Navigation