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Prostaglandin F2a (PGF2a): an inadequate marker of the vitality of wounds?

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Summary

We have studied the viability of (PGF2a): as a vitality marker in skin wounds. Incised vital skin wounds and homolateral control pieces of skin were obtained from 20 autopsies performed at the Institute of Legal Medicine of Coimbra University (Portugal). We have also studied 10 fresh skin samples from the Department of Dermatology of the University Hospital (Granada). Our results show that (PGF2a): is not suitable for the diagnosis of the vitality of wounds because of its irregular behaviour.

Zusammenfassung

Die Verwendbarkeit von Prostaglandin F2a als Vitalitätsmarker wurde an Hautverletzungen studiert. Als Material dienten 20 vitale Schnittverletzungen sowie entsprechende Kontrollen unverletzter Haut aus 20 Obduktionsfällen des Instituts für Rechtsmedizin der Universität Coimbra (Portugal). Weiter wurden 10 frische Hautproben von Patienten der Dermatologischen Abteilung des Klinikums Granada untersucht. Die Prostaglandin-Analysen wurden mittels RIA durchgeführt. Die Ergebnisse belegen, daß die Bestimmung des (PGF2a): nicht als Methode des Vitalitätsnachweises von Wunden geeignet ist.

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Authors and Affiliations

  1. Department of Legal Medicine and Toxicology, Faculty of Medicine, University of Granada, E-18071, Granada, Spain

    C. Hernández-Cueto, E. Girela, M. D. Calvo & E. Villanueva

  2. Institute of Legal Medicine, University of Coimbra, 3000, Coimbra, Portugal

    D. N. Vieira, E. Marques & F. Oliveira de Sà

  3. Laboratory of Medical Research and Tumoral Biology, Faculty of Medicine, University of Granada, E-18071, Granada, Spain

    M. Villalobos

Authors
  1. C. Hernández-Cueto
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  2. D. N. Vieira
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  3. E. Girela
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  4. E. Marques
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  5. M. D. Calvo
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  6. M. Villalobos
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  7. F. Oliveira de Sà
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  8. E. Villanueva
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Hernández-Cueto, C., Vieira, D.N., Girela, E. et al. Prostaglandin F2a (PGF2a): an inadequate marker of the vitality of wounds?. Int J Leg Med 106, 312–314 (1994). https://doi.org/10.1007/BF01224777

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  • DOI: https://doi.org/10.1007/BF01224777

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