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Mediastinal infusion of epirubicin and 5-fluorouracil. A complication of totally implantable central venous systems. Report of a case

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  • Clinical Oncology
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Abstract

Perforation of the wall of the superior vena cava by a central venous catheter is reported. The resultant inadvertent infusion of 5-fluorouracil and epirubicin caused a severe acute inflammatory reaction in the right-lobe bronchus, mediastinal infiltration and pleural and pericardial effusions. The patient recovered but has residual mild oesophageal dysfunction.

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References

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Authors and Affiliations

  1. Department of Internal Medicine-Oncology, Hotel-Dieu, 1 Place du Parvis Notre-Dame, 75181, Paris Cedex 04, France

    J. M. Rodier, E. Pujade Lauraine, L. Batel-Copel & A. Bernadou

  2. Department of Radiology, Hotel-Dieu, 1 Place du Parvis Notre-Dame, 75181, Paris Cedex 04, France

    L. Malbec

Authors
  1. J. M. Rodier
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  2. L. Malbec
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  3. E. Pujade Lauraine
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  4. L. Batel-Copel
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  5. A. Bernadou
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Rodier, J.M., Malbec, L., Lauraine, E.P. et al. Mediastinal infusion of epirubicin and 5-fluorouracil. A complication of totally implantable central venous systems. Report of a case. J Cancer Res Clin Oncol 122, 566–567 (1996). https://doi.org/10.1007/BF01213554

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  • DOI: https://doi.org/10.1007/BF01213554

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