Abstract
The effect was investigated of endurance training on the expression of uncoupling protein (UCP) mRNA in brown adipose tissue (BAT) of rats. The exercised rats were trained on a rodent treadmill for 5 days per week and a total of 9 weeks. After the training programme, a marked decrease in BAT mass was found in terms of weight or weight per unit body weight; there was a corresponding decrease in DNA content and a downward trend in RNA and glycogen levels. The UCP mRNA was present at a markedly decreased level in BAT of trained animals. In consideration of the reduced levels of mRNAs for hormone-sensitive lipase and acylCoA synthetase, the brown adipose tissue investigated appeared to be in a relatively atrophied and thermogenically quiescent state.
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Yamashita, H., Yamamoto, M., Sato, Y. et al. Effect of running training on uncoupling protein mRNA expression in rat brown adipose tissue. Int J Biometeorol 37, 61–64 (1993). https://doi.org/10.1007/BF01212769
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DOI: https://doi.org/10.1007/BF01212769