Abstract
We report on a 37-year-old female patient with generalised giant-cell tumour of the bone, whose tumour was refractory to conventional chemotherapy. Subsequent treatment with interferon α2a in increasing dosage from 4×106 IU (three times a week) to 9×106 IU (three times a week) led to a significant decrease of pulmonary metastases and a stabilisation of the disease after 12 months of treatment. In progressive chemotherapy refractory giant-cell tumour interferon α2a may be of therapeutic benefit.
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Kaiser, U., Neumann, K. & Havemann, K. Generalised giant-cell tumour of bone: Successful treatment of pulmonary metastases with interferon α, a case report. J Cancer Res Clin Oncol 119, 301–303 (1993). https://doi.org/10.1007/BF01212729
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DOI: https://doi.org/10.1007/BF01212729