Abstract
Helicobacter pylori in the stomach is an etiological factor of gastritis and peptic ulcer. It is now considered that gastric cancer can be, at least in some cases, a late complication ofH. pylori infection. In 123 consecutive endoscopic antral biopsies obtained from patients with the OkamotsoHospital, the specimens were subjected to the rapid urease test (RUT), histology (H&E stain), and culture, for the identification ofH. pylori. The results of these methods were compared semi-quantitatively in order to evaluate these detection methods for identifyingH. pylori. The results of these methods were found to agree well, with the Spearman's rank correlation coefficient between RUT and culture being 0.90 (P<0.01) and that between histology and culture being 0.80 (P<0.01). RUT is considered to be a very simple, sensitive, and highly specific test which enables the endoscopist to diagnoseH. pylori infection.
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Kawanishi, M., Fukuda, S., Kawaguchi, H. et al. Significance of rapid urease test for identification ofHelicobacter pylori in comparison with histological and culture studies. J Gastroenterol 30, 16–20 (1995). https://doi.org/10.1007/BF01211369
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DOI: https://doi.org/10.1007/BF01211369