Abstract
Standard electro-oculography was performed in 10 patients with malignant unilateral uveal melanoma All eyes were treated by means of surgical local excision. After a mean ± standard deviation follow-up of 10.5 ± 5.5 months (range, 6 to 20 months) in the five patients with choroidal melanoma, the electro-oculographic recordings, which had appeared reduced or flat before the surgery, increased significantly just after the local excision. Thereafter the amplitudes of the electro-oculographic light peaks were reduced in all cases up to extinction, possibly because of a retinal detachment. On the contrary, the electro-oculographic value in the five melanomas localized at the iris and ciliary body, normal before the surgery, showed a marked and persistent increase after surgery, probably related to an ‘electric hole’ in the globe.
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Abbreviations
- AI:
-
Arden index
- EOG:
-
electro-oculogram
References
Bohar A, Farkas A. Comparative electrophysiological observation of intraocular tumors and retinal detachment. Doc. Ophthalmol Proc Ser 1976; 10: 399–403.
Ponte F, Lauricella M. On the lack of correlation between ERG and EOG alteration in malignant melanoma of choroid. Doc Ophthalmol Proc Ser 1976; 13: 87–92.
Staman JA, Fitzgerald CR, Dawson WVV, Barris MC, Hood I. The EOG and choroidal malignant melanomas. Doc Ophthalmol Proc Ser 1980; 49: 201–9.
Markoff JI, Shakin E, Shields JA, Augsberger JJ. The electro-oculogram in eyes with choroidal melanoma. Ophthalmology 1981; 88: 1122–5.
Jones RM, Klein R, de Venecia G, Myers FL. Abnormal electrooculograms from eyes with a malignant melanoma of the choroid. Invest Ophthalmol Vis Sci 1981; 20: 276–9.
Markoff JI, Shakin E, Shields JA, Augsberger JJ. The electrooculogram in presumed choroidal melanomas and nevi. Doc Ophthalmol Proc Ser 1982; 31: 105.
Balestrazzi E, Marullo M, Blasi MA. Pars plana vitrectomy in the conservative surgery of uveal melanomas. In: Proceedings of the Third International Symposium on Vitreo-Retinal Surgery Retinopathy, Rome, Italy, Ed. Retina, 1991; 389–92.
Arden GB, Kelsey JH. Changes produced by light in the standing potential of the human eye. J Physiol Lond 1962; 161: 189–204.
Balestrazzi E, Delle Noci N, Pintucci S, Spadea L, Marullo M, Blasi MA. La terapia chirurgica dei melanomi endobulbari e dei retinoblastomi. In: Proceedings of XX Convegno Società Oftalmologica Meridionale, Bari, Italy, 1986, 171–94.
Foulds WS. The local excision of choroidal melanoma. Trans Ophtalmol Soc UK 1977; 97: 412–5.
Thaler A, Lessel My Heilig P. The slow oscillation in malignant choroidal melanoma. Doc Ophtalmol Proc Ser 1989; 71: 403–7.
Alexandridis E. Extraretinal influences on the EOG potential. Bibl Ophthalmol 1976; 88: 86–93.
Blach RK, Behrman Y. The electrical activity of the eye in retinal detachment. Trans Ophthalmol Soc UK 1967; 87: 263–6.
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Spadea, L., D'amico, M., Dragani, T. et al. Electro-oculographic changes after local excision of uveal melanoma. Doc Ophthalmol 86, 239–245 (1994). https://doi.org/10.1007/BF01203547
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DOI: https://doi.org/10.1007/BF01203547