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In vitro cellular responses to a non-ionic surfactant, Pluronic F-68

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Summary

The effects of a non-ionic surfactant, Pluronic F-68, on growth of chick embryonic fibroblasts and hamster melanoma cellsin vitro have been studied. Low concentrations (0.05–0.1% w/v) of commercial grade Pluronic stimulated growth of both cell types whereas low concentrations of purified Pluronic inhibited fibroblast growth but strongly stimulated growth of melanoma cells. These observations suggest that Pluronic may have value for regulating growth of cell cultures.

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Authors and Affiliations

  1. Department of Zoology, University of Nottingham, University Park, NG7, 2RD, Nottingham, UK

    P. Karen Bentley, Richard M. C. Gates, Kenneth C. Lowe, David I. de Pomerai & J. A. Lucy Walker

Authors
  1. P. Karen Bentley
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  2. Richard M. C. Gates
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  3. Kenneth C. Lowe
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  4. David I. de Pomerai
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  5. J. A. Lucy Walker
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Karen Bentley, P., Gates, R.M.C., Lowe, K.C. et al. In vitro cellular responses to a non-ionic surfactant, Pluronic F-68. Biotechnol Lett 11, 111–114 (1989). https://doi.org/10.1007/BF01192184

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