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State of synapses of the cortex of cerebral hemispheres on γ-irradiation

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Abstract

In adult rats with developing neurological disorders we detected destructive changes in most of the synapses of the brain sensorimotor cortex 1.6–4.3 h after a single dose of γ-irradiation (200 Gy). All functionally important parts on the axonal and dendritic sides of the synapses had undergone changes: mitochondria, synaptic vesicles, pre- and postsynaptic membranes, synaptic complexes, and subsynaptic consolidations, axonal and dendritic plasma, and their inclusions. These changes possibly cause disconnection of the neurons and provide a structural basis for neurological deficiencies following a high substantial ionizing radiation.

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Authors and Affiliations

  1. Moscow

    N. A. Gaidamakin & I. B. Ushakov

Authors
  1. N. A. Gaidamakin
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  2. I. B. Ushakov
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Translated from Zhurnal Nevrapatologii i Psikhiatrii imeni S. S. Korsakova, Vol. 88, No. 7, pp. 11–16, July, 1988.

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Gaidamakin, N.A., Ushakov, I.B. State of synapses of the cortex of cerebral hemispheres on γ-irradiation. Neurosci Behav Physiol 19, 483–488 (1989). https://doi.org/10.1007/BF01181863

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  • DOI: https://doi.org/10.1007/BF01181863

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