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Disturbance of neuroendocrine regulation of sexual behavior of male rats with streptozotocin diabetes

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Conclusions

  1. 1.

    A decrease in the level of activity of both motivational and copulatory components of sexual behavior was observed during the development of experimental diabetes following the administration of streptozotocin to rat males.

  2. 2.

    The concentration of LHRH in diabetic rats decreased in the ME [sic], and similar changes were recorded in both the PA and the MBH when it was determined in the synaptosomal fraction of the hypothalamus.

  3. 3.

    The concentration of nuclear E2 receptors was increased in the APA at the level of the hypothalamus, whereas the number of testosterone-binding sites did not differ from the values of the control group.

  4. 4.

    The level of LH and FSH in the blood of the rats did not change during the development of diabetes, the concentration of PRL and T decreased, and that of E2 increased.

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Authors and Affiliations

  1. Laboratory of Endocrine System Physiology of the Endocrinological Scientific Center, Russian Academy of Medical Sciences, Moscow

    T. V. El'tseva, E. I. Adamskaya, T. A. Peryshkova & V. N. Babichev

Authors
  1. T. V. El'tseva
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  2. E. I. Adamskaya
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  3. T. A. Peryshkova
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  4. V. N. Babichev
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Additional information

Translated from Problemy Éndokrinologii, Vol. 38, No. 6, pp. 46–50, November–December, 1992.

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El'tseva, T.V., Adamskaya, E.I., Peryshkova, T.A. et al. Disturbance of neuroendocrine regulation of sexual behavior of male rats with streptozotocin diabetes. Neurosci Behav Physiol 23, 538–544 (1993). https://doi.org/10.1007/BF01153681

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  • DOI: https://doi.org/10.1007/BF01153681

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