Abstract
The molecular encapsulation of sodium perfluoroctanoate (SPFO) by hydroxypropyl-β-cyclodextrin (HP-β-CD) or 2,6-di-O-methyl-β-cyclodextrin (DM-β-CD) has been analyzed by measuring the conductivity in solution of the ternary systems formed by CD + SPFO + H2O. The studies were carried out at 25 °C using a fully computerized electrical conductivity technique. The measurements were made as a function of CD concentration at various non-micellar concentrations of SPFO, and as a function of CD and SPFO concentrations with [CD]/[SPFO] constant at stoichiometric ratio. The inclusion complexes, HP-β-CD-SPFO and DM-β-CD-SPFO, were characterized through the stoichiometry, which has been found to be 1 : 1 in both cases, and the binding constants, which have been evaluated from the conductivity data with a model proposed by us considering the variation of the ionic molar conductivities with the concentration and the association of the surfactant counterion to the inclusion complex. The resultingK values indicate that the interaction between the CD cavity and the monomeric SPFO is strong and similar in both cases.
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References
M.L. Bender and M. Komiyarna:Cyclodextrin Chemistry, Springer-Verlag, Berlin (1978).
J. Szejtli:Cyclodextrins and their Inclusion Complexes, Academiai Kiado, Budapest (1982).
W. Saenger: in J.L. Atwood, J.E.D. Davies, and D.D. MacNicol (Eds.),Inclusion Compounds, Vol. 2, Academic Press, London (1984).
R.J. Clarke, J.H. Coates, and S.F. Lincoln:Adv. Carbohydr. Chem. Biochem. 46, 205 (1988).
D. Duchêne:Cyclodextrins and their Industrial Uses, Ed. de Santé, Paris (1987).
J. Szejtli:Carbohydr. Polym. 12, 375 (1990).
D. Duchêne and D. Wouessidjewe:Drug. Dev. Ind. Pharm. 16, 2487 (1990).
J. Szejtli:J. Incl. Phenom. 14, 25 (1992).
K.H. Fröming and J. Szejtli:Cyclodextrins in Pharmacy, Kluwer Acad. Pub., Dordrecht (1993).
R. Palepu and V.C. Reinsborough:Can. J. Chem. 67, 1550 (1989).
R. Palepu, J.E. Richardson, and V.C. Reinsborough:Langmuir 5, 218 (1989).
W. Guo, B.M. Fung, and S.D. Christian:Langmuir 8, 446 (1992).
E. Junquera, G. Tardajos, and E. Aicart:Langmuir 9, 1213 (1993).
E. Saint Aman and D. Serve:J. Colloid Interface Sci. 138, 365 (1990).
D.J. Jobe, R.E. Verrall, E. Junquera, and E. Aicart:J. Phys. Chem. 98, 10814 (1994).
E. Junquera and E. Aicart:Rev. Sci. Instrum. 65, 2672 (1994).
E. Junquera, L. Pena, and E. Aicart:Langmuir 11, 2685 (1995).
D.A. Derenlau:J. Am. Chem. Soc. 91, 4044 (1969).
S. Kato, S. Harada, H. Nakashima, and H. Nomura:J. Colloid Interface Sci. 150, 305 (1992).
L. Pena, E. Junquera, and E. Aicart:J. Solution Chem. 24, 1075 (1995).
E. Junquera, J.G. Benito, L. Pena, and E. Aicart:J. Colloid Interface Sci. 163, 355 (1994).
R.A. Robinson and R.M. Stokes:Electrolyte Solutions, Butterworths, London (1965).
U. Tinner:Elechodes in Potentiometry, Metrohm AG, Herisau (1989).
J. Kielland:J. Am. Chem. Soc. 59, 1675 (1937).
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Junquera, E., Peña, L. & Aicart, E. Conductivity studies of the molecular encapsulation of sodium perfluoroctanoate byβ-cyclodextrin derivatives. J Incl Phenom Macrocycl Chem 24, 233–239 (1996). https://doi.org/10.1007/BF01133381
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DOI: https://doi.org/10.1007/BF01133381