Abstract
Women with absent or dysfunctional uteri consented to controlled ovarian stimulation, ovum aspiration, in vitro fertilization, and embryo culture. Cleaving preembryos were transferred to recipient (surrogate) women whose menstrual cycles were in approximate synchrony with the ovum donor. None of the embryo recipients received medication. Six cases are described, resulting in one spontaneous loss at 6 weeks, four full-term deliveries, and one ongoing pregnancy. HLA typing demonstrated all babies to be genotypic offspring of the gamete donors.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Utian WH, Sheean LA, Goldfarb JM, Kiwi R: Successful pregnancy after in vitro fertilization and embryo transfer from an infertile woman to a surrogate. N Engl J Med 1985;313:1351–1352
Utian WU, Goldfarb JM, Sheean LA: Implementation of an IVF program. J Vitro Fert Embryo Transfer 1984;1:72–75
Rosenwaks Z: Donor eggs: Their application in modern reproductive technologies. Fert Steril 1987;47:895
Ahuja KK, Smith W, Tucker M, Craft I: Successful pregnancies form transfer of pronuclear embryos in an outpatient in vitro fertilization program. Fert Steril 1985;44:181
Craft I, Djahanbakhch O, McLeod F, Bernard A, Green S, Twigg H, Smith W, Lindsey K, Edmonds K: Human pregnancy following oocyte and sperm transfer to the uterus. Lancet 1982;I:1031
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Sheean, L.A., Goldfarb, J.M., Kiwi, R. et al. In vitro fertilization (IVF)-surrogacy: Application of IVF to women without functional uteri. J Assist Reprod Genet 6, 134–137 (1989). https://doi.org/10.1007/BF01130776
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF01130776